561 Tablet Manufacturing and Processes Modelling

Wednesday, November 18, 2020: 8:00 AM - 9:00 AM
Pharmaceutical Discovery, Development and Manufacturing Forum (26) (PreRecorded+)

Description:
This session will cover in silico simulations of tablet manufacturing processes, including drying, coating, mixing, dissolution behavior, etc. Modeling approaches include CFD, DEM, PBM, SPH and other methods.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Chair:
Ebenezer Ojo Email: ebenezer.ojo@strath.ac.uk
Co-chairs:
Kushal Sinha Email: kushal.sinha@abbvie.com
Shrikant Swaminathan Email: shrikant_swaminathan@amat.com


(561a) Simulation of Drying of Pharmaceutical Wet Granules in a Fluidized Bed Dryer Using Coupled CFD-DEM Approach
Syed Ahsan, Hossain Aziz, Bodhisattwa Chaudhuri and Yijie Gao


(561c) Continuum Simulations of Heat and Mass Transfer in Wet Granular Mixtures
Viraj Vilas Belekar, Nandkishor K. Nere, Kushal Sinha, Theodore J. Heindel and Shankar Subramaniam


(561d) New Insights into Local Residence Time Distributions of Twin Screw Elements Used in Hot Melt Extrusion Via Smoothed Particle Hydrodynamics Simulation
Hannes Bauer, Josip Matić and Johannes G. Khinast


(561e) Towards a Generic Model for Twin-Screw Wet Granulation: Calibration and Validation of an Improved PBM for Multiple APIs.
Ana Alejandra Barrera Jiménez, Daan Van Hauwermeiren, Michiel Peeters, Ingmar Nopens and Thomas De Beer


(561f) Developing a Digital Twin for the L.B. Bohle Tablet Coating Process
Alfred Berchielli, Ismail Anifowoshe, Sandra Conway, Pankaj Doshi, Naomi Hodgins, Reza Kamyar, Peiyuan Liu, Bruce C. MacDonald, Zilong Wang, Gopal Kasat, Mothivel Mummudi, Parth Sinha and Andreas Altmeyer


(561g) Implementation of a Dynamic Mechanistic Model Towards Optimal Design and Scale-up of an Atypical Freeze-Drying Process
Maitraye Sen, Lindsay Wegiel, Joao Moreira and Pavol Rajniak
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
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