157 Poster Session: Bioengineering

Tuesday, November 17, 2020: 8:00 AM - 9:00 AM
Food, Pharmaceutical & Bioengineering Division (15) (Poster Gallery)

Description:
This poster session highlights experimental, theoretical, and computational advances in bioengineering research. This includes, but is not limited to; biocatalysis and biobased products; cell culture engineering and biomanufacturing; metabolic engineering; protein science and engineering; biosensors and biodiagnostics; synthetic biology; systems and quantitative biology; and bioinformatics. We encourage the submission of high quality abstracts that describe quantitatively and specifically the research work to be presented.

Sponsor:
Bioengineering
Co-Sponsor(s):
Poster Sessions (POSTERSESSIONS)
Chair:
Nicholas R. Sandoval Email: nsandova@tulane.edu
Co-chairs:
J. Andrew Jones Email: jones@miamioh.edu
Jason T. Boock Email: boockj@MiamiOH.edu
Maryam Raeeszadeh-Sarmazdeh Email: maryamr@unr.edu
Aditya Sarnaik Email: asarnaik@asu.edu
Shelby Brooks Email: sgbrooks@crimson.ua.edu


Biocatalysis and Biobased Products


(157a) An Autoinducible Fungus to Increase Production of Biofuels and Bioproducts
Amin Zargar, Jenny Landberg, Amanda Hernandez, Jessica Wang, Samantha Chang and Jay Keasling


(157c) Integrating Bisphenol a Degradation Function into Shewanella Oneidensis
Jiacheng Zhou, Gregg P. Kotchey, David V. P. Sanchez and Seok Hoon Hong


(157d) Biological Conversion of Methane into Polyhydroxybutyrate (PHB)
Letícia Oliveira Bispo Cardoso, Bruno Karolski, Louise Hase Gracioso, Bruna Bacaro Borrego, Elen Aquino Perpetuo and Claudio A.O. Nascimento


(157e) Extracellular Carotenoid Production from Microalgae Under Increased CO2 Concentrations
Priscila C.C. Jesus, Maria Anita Mendes, Thiago O. Basso, Elen A. Perpetuo and Claudio A.O. Nascimento


Cell Culture Engineering and Biopharmaceutical Manufacturing


(157h) Sialic-Acid Analogs for the Attenuation of A-beta Toxicity
Dhruva Dhavale, Hy Lai and James Henry


(157i) Agitation in a Microcarrier-Based Spinner Flask Bioreactor Modulates Homeostasis of Human Mesenchymal Stem Cells
Richard Jeske, Shaq Lewis, Ang-Chen Tsai, Kevin Sanders, Xuegang Yuan and Yan Li


(157j) Retinal Photoreceptor Differentiation from Human Pluripotent Stem Cells for 3-D Bio-Printing
Shallu Kutlehria, Mark Marzano, Peggy Arther, Yan Li and Mandip Singh


(157k) Compounds to Modify Plaque Formation and Toxicity of A-beta in Alzheimer’s Disease
Hy Lai and James Henry


(157l) Membrane Protein Antibody Discovery Using Yeast-Surface Display and Whole Cell Selections in Suspension
Patrick J. Krohl, Kook Bum Kim and Jamie B. Spangler


(157m) Extended 3D Cancer Cell Migration in Response to an Oscillating Chemical Gradient Breaks the Spatial Range Limitations of Conventional Chemotaxis
Sharif M. Rahman, Joshua M. Campbell, Kyle Elee and Adam T. Melvin


(157n) Tobacco Cell-Secreted Hematopoietic Growth Factors for Ex Vivo Production of Red Blood Cells
Jianfeng Xu


(157o) A Dynamic Elementary Flux Mode-Based Model for Antibody Producing Cell Lines and Model Based Evaluation of Fed-Batch Cultures
Denizhan Yilmaz, Satish J. Parulekar and Ali Cinar


(157p) Polymer Amphiphiles for Directed Self-Assembly Around Hepatitis B Virus Particles
Mark Pitman, Lauren Maghak and Jessica Larsen


(157q) Cycling Aggregation and Planar Culture Extends in Vitro Expansion Potential of Human Mesenchymal Stem Cells
Brent Bijonowski, Richard Jeske, Yan Li and Samuel C. Grant


(157r) Analyzing the Role of Chinese Hamster Ovary Extracellular Vesicles (CHO-EVs) in Extracellular Communication, Cellular State, and Protein Expression of CHO Cultures
Jessica Belliveau and Eleftherios T. Papoutsakis


(157s) Targeted Gene Therapy of Hematopoietic Stem and Progenitor Cells Using Cas9 and siRNA-Loaded Megakaryocytic Membrane Vesicles
Samik Das and Eleftherios T. Papoutsakis


(157t) How Is Hydrocephalus Treatment Dependent on Astrocyte Phenotype Expression?
Fatemeh Khodadadei and Carolyn Harris


(157v) A Mechanistic Analysis of Recombinant Adeno-Associated Virus Productivity in Biomanufacturing
Sha Sha, Tam Nguyen, Andrew J. Maloney, Caleb Neufeld, Georgios Katsikis, Paul W. Barone, Jacqueline Wolfrum, Stacy Springs, Scott Manalis, Anthony J. Sinskey and Richard Braatz


(157w) Biocompatibility and Potential Regenerative Effects of Sugarcane Derivatives in a 2D Skin Wound Model
Monica Cuellar, Julian Andres Serna, Jader Rodriguez, Sebastian Escobar, Juan C Cruz and Carolina Muñoz Camargo


Protein Science and Engineering


(157x) Engineering Superior VEGF Antagonists to Treat Retinal Diseases
Paul R. Sargunas, Rakeeb Kureshi and Jamie B. Spangler


(157y) Predicting Antibody Developability from Molecular Simulations and Machine Learning
Pin-Kuang Lai


(157z) Self-Assembled Cgamp-Stingδtm Signaling Complex As a Bioinspired Platform for Cgamp Delivery
Yanpu He, Celestine Hong, Emily Yan, Samantha Fletcher, Ge Zhu, Mengdi Yang, Yingzhong Li, Xin Sun, Jiahe Li, Darrell Irvine and Paula T. Hammond


(157aa) Process Analytical Technologies for Recombinant Adeno-Associated Virus-Based Gene Therapy
Andreas Gimpel, Georgios Katsikis, Sha Sha, Andrew J. Maloney, Moo Sun Hong, Tam Nguyen, Jacqueline Wolfrum, Stacy Springs, Anthony J Sinskey, Scott Manalis, Paul W. Barone and Richard Braatz


(157ab) Bacterial Expression of Moringa Oleifera Seed Proteins for Virus Filtration
Brielle Hohne and Manish Kumar


(157ac) Machine Learning Guides Combinatorial Protein Library Design
Mehrsa Mardikoraem and Daniel Woldring


(157ad) Allosteric Regulation of GPCRs Driven By Engineered Protein Scaffolds
Zahra Aayanifard and Daniel Woldring


Biosensors and Biodiagnostics


(157af) Analysis of Organophosphate Residue Detection on SOLID Surface Using QCM-D As BIO-Sensing Platform
Shalini Shikha and Sudip Pattanayek


(157ag) Tuning the Cell-Free Protein Synthesis System for the Development of Highly Sensitive Biosensors
Caroline E. Copeland, Jeehye Kim and Yong-Chan Kwon


(157ah) Engineered Heterobivalent Protein Ligands Enable Early Detection of Disease
Sunanda Dey, David Hickey and Daniel Woldring


(157ai) Foodborne Pathogen Detection: Identification of Protein Catalyzed Capture Agents Targeting E. coli O157:H7
Alexander Winton, An Ngo, Wais Mojadedi and Matthew Coppock


(157aj) Development and Characterization of an E. coli-based Vitamin C Biosensor
Fernanda Piorino and Mark P. Styczynski


Metabolic Engineering


(157ak) Metabolic Engineering of Microbes for the Green Production of C2-C6 Diols.
Zhen Chen


(157al) Genome-Scale Metabolic Modeling of Clostridium thermocellum for Omics Integration and Modular Cell Design
Sergio Garcia, R Adam Thompson, Richard J. Giannone, Satyakam Dash, Costas Maranas, Cong T. Trinh and Will Khomtchenko


(157ap) Designing Microbial Co-Culture Systems for Designer Ester Biosynthesis
Hyeongmin Seo and Cong T. Trinh


(157aq) Yeast Metabolic Engineering for Fermentation of Pectin Monomers
Deokyeol Jeong, Heeyoung Park and Soo Rin Kim


(157ar) Leveraging the Hermes Transposon to Accelerate the Development of Nonconventional Yeast-Based Microbial Cell Factories
Yuxin Zhao, Zhanyi Yao, Deon Ploessl, Saptarshi Ghosh, Meirong Gao, Mingfeng Cao and Zengyi Shao


(157as) Hexanoic Acid Production from Syngas and Glucose By a Newly Isolated Strain Clostridium Sp. JS66
Joongsuk Kim, Kyungsik Kim, Ja Kyong Ko, Sun-Mi Lee, Gyeongtaek Gong, Kyoung Heon Kim and Youngsoon Um


(157ao) Aerobic Ester Production through Escherichia coli-Clostridium Co-Culture
Yonghao Cui, Xiaoqiang Ma, Jianzhong He, Yang Kun-Lin and Kang Zhou


Synthetic Biology and Applications


(157av) Synthesis and Application of Cell-Free Synthesized Therapeutic Human Proteins
Jeehye Kim, Caroline E. Copeland and Yong-Chan Kwon


(157ay) Modifying the Operator for More Dynamic Tunable Gene Expression in Paraburkholderia Sacchari.
Dianna Long, Cheryl Immethun and Rajib Saha


(157az) Regulation of Gene Expression in E. coli Using Theophylline Sensing Riboswitches
Alexandra Wrist and Ryan M. Summers


Systems and Quantitative Biology


(157bb) Acetate Switch in Methanococcus Maripaludis S2
Chi Hung Vo, Nishu Goyal, Iftekhar A. Karimi and Markus Kraft


(157bc) A Rab Escort Protein in Yeast Regulates the MAPK Pathway That Controls Filamentous Growth
Sheida Jamalzadeh, Paull Cullen and Heather Dionne


(157bd) Genetic and Regulatory Basis of Temporal Variation in Complex Traits
Christopher M. Jakobson and Daniel F. Jarosz


(157bg) Regulation of Pancreatic Regenerating Protein (Reg) Expression By Microrna-7
Zijing Chen, Fan Zhang, Shawna Downing and Emmanuel S. Tzanakakis


(157bh) Bioorthogonal Noncanonical Amino Acid Tagging (BONCAT) Enables Cell-Selective Proteomic Profiling in Complex Biological Systems
Xinran Liu


(157bi) Engineering the Bioavailability of Sulfur to Control Iron Redox States in Acidithiobacillus Ferrooxidans
Yuta Inaba, Alan West and Scott Banta


(157bj) Persulfide and Polysulfide-Induced Posttranslational Protein Modifications in Oleaginous Rhodococcus Jostii RHA1
Xiaolu Li, Wei-Jun Qian and Bin Yang


(157bk) A Mathematical Model of the Glomerular Filtration Barrier in Diabetic Kidney Disease
Duncan H. Mullins and Ashlee N. Ford Versypt


(157bl) Computational Modeling for Designing a Device Harboring Optogenetically Engineered Pancreatic Beta-Cells
Zijing Chen, Leah Truskinovsky and Emmanuel S. Tzanakakis


(157bm) Investigation of Incidents and Trends of Antimicrobial Resistance in Foodborne Pathogens in Eight Countries from Historical Sample Data
Katherine Yang, Annie Wang, Matthew Fu, Aaron Wang, Kevin Chen, Qian Jia and Zuyi (Jacky) Huang


(157bn) Deep Learning-Aided Intelligent Flow Cytometry for Label-Free Cell Detection
Jawahar Khetan and Dipak Barua


(351as) Experimental Design Algorithm for Efficient Optimization of Culture Media
Zachary Cosenza and David E. Block
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