426 Mixing Scale-Up and Scale-Down Issues in Pharmaceutical Processes

Wednesday, November 18, 2020: 8:00 AM - 9:00 AM
North American Mixing Forum (06) (PreRecorded+)

Description:
Mixing issues and scale-up/scale-down strategies for the production of pharmaceutical and biopharmaceuticals.

Sponsor:
North American Mixing Forum
Co-Sponsor(s):
Pharmaceutical Discovery, Development and Manufacturing Forum (26)
Chair:
Luis Sierra Email: luis_sierra2@merck.com
Co-chairs:
Otute Akiti Email: otute.akiti@gmail.com
Piero M. Armenante Email: piero.armenante@njit.edu


(426a) Towards an Understanding of Fluid and Particle History in a Turbulent Mixing Tank Using Large Eddy Simulation: Examining Effect of Different Impeller Types.
Matthew H. Flamm and Katherine Raudenbush


(426b) Building the Predictive Process Engineering Toolbox to Define Mixing Parameters for Early-Stage Drug Product Manufacturing of Large Molecules
Robert Kuo, Zbynek Kalal, Julia Eckhoff, Smeet Deshmukh, Matthew H. Flamm, Sachin Mittal and Adam Procopio


(426c) Hold Tank Mixing Profile Optimization for Potency Control in Filling a Shear Thinning Suspension Formulation
Richard Shields


(426d) Efficient Process Development in the Micromixing-Mesomixing Space: The Bourne Protocol and Beyond
Aaron Sarafinas


(426e) Development of a Mixing Index Provides a Means to Solve Many Industrial Mixing Problems
David S. Dickey


(426f) Implementation of a Vapor-Liquid Equilibrium and Vapor Purge Model for Scale-up of a Transfer Hydrogenation
Kira Ragazzo, Federico Lora Gonzalez, Zhongping Shi, Ronald Carrasquillo-Flores and Shawn Brueggemeier


(426g) Coupling Reaction Kinetics, Calorimetry and Mixing Studies for Successful Scale-up of Exothermic Reactions
Filipe Ataíde, João Sardinha, Ricardo Mendonça, Elsa Gonçalves, Ana Monteiro and Susana Nascimento
See more of this Group/Topical: North American Mixing Forum
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