601 Particle Formation and Crystallization Processes from Liquids, Slurries, and Emulsions

Tuesday, November 17, 2020: 8:00 AM - 9:00 AM
Separations Division (02) (PreRecorded+)

Description:
This Session encompasses aspects of solid-liquid separation dealing with crystallization and crystal growth from solution, crystal morphology, effects of impurities, solvents and particulates, particle engineering, particle-process modeling and control, particle surface properties, interfacial effects, and emulsion crystallization. Papers covering experimental or theoretical aspects, and industrial case studies are welcome.

Sponsor:
Crystallization and Evaporation
Co-Sponsor(s):
Food, Pharmaceutical & Bioengineering Division (15), Particle Production and Characterization (03A)
Chair:
Fredrik Nordstrom Email: fredrik.nordstrom@boehringer-ingelheim.com
Co-Chair:
Manish S. Kelkar Email: manish.kelkar@abbvie.com


(601a) Improvement of Drug Substance Bulk Powder Properties through Process Crystallization
Otute Akiti, Kate Donnelly, Niamh McKeever and Lori Jean van Orden


(601b) Singly‑Twinned Growth of Si Crystals upon Chemical Modification
Saman Moniri and Ashwin J. Shahani


(601c) Elucidating the Influence of Hydroxycitrate on Brushite Crystallization Via Bulk and Interfacial Studies
Ma. Charlene Tapia, Naoyuki Miyashita, Wei Weilin, Kazuki Miyata, Takeshi Fukuma, Jem Valerie D. Perez and Bryan G. Alamani


(601d) Islatravir Penultimate Step Crystallization: Purification of an API in the Presence of High Protein Loading from an Enzymatic Cascade
Eric Margelefsky, Sandra A. Robaire, Shane T. Grosser, Thomas T. Kwok, Maggie Miller, Jacob Heltzel, Kevin Sirk, Keith A. Mattern, Jacob H. Forstater, Whittaker Aaron, Gregory Hughes and Anne Mohan


(601e) Development of a Crystallization Process for the Final Step of the Biocatalytic Synthesis of Islatravir
Eric Sirota


(601f) Impact of the Process Conditions of an Evaporation to Dryness Operation Performed in a Conical Screw Vacuum Dryer on the Isolated Product Psd: Lab- and Pilot-Scale Studies
Sélim Douieb, Benjamin Lorenzini, Georges Assaf and Ugo Cocchini


(601g) A Generalized Approach for Rapid Aqueous MOF Synthesis By Controlling Solution pH
Luke Huelsenbeck, Hongxi Luo, Prince Verma, Jillian Dane, Rachel Ho, Emily Beyer, Hailey Hall, Geoffrey M. Geise and Gaurav Giri
See more of this Group/Topical: Separations Division
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