599656 Revolutionize of Pharmaceutical Product Changeovers By Enhanced Cleaning with Microbubbles

Monday, November 16, 2020
Pharmaceutical Discovery, Development and Manufacturing Forum (26) (Poster Gallery)
William B. Zimmerman, Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, United Kingdom and Joan Cordiner, Chemical and Biological Engineering, University of Sheffeld, Sheffield, United Kingdom

Pharmaceutical, Biopharmaceutical, Agrochemical and Specialty chemical companies make many different products in their plants. This is true both for the active ingredient stages as well as the secondary of formulation processing. Cleaning and set up between products is critical and reduce productivity time up to 50% in some cases. Microbubbles have been shown to enhance many unit operations e.g. distillation. The benefits of microbubbles in cleaning will be presented along with the impact this will enable in regulatory/ registration processes.

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