400 Continuous Processing in the Manufacture of Pharmaceuticals: Drug Product II

Tuesday, November 15, 2016: 3:15 PM - 5:45 PM
Continental 4 (Hilton San Francisco Union Square)
Description:
Continuous Processing in the Manufacture of Pharmaceuticals: Drug Product Continuous manufacturing is a new paradigm in the pharmaceutical industry. In the recent years, a number of pharmaceutical companies, academic institutions and the equipment/technology providers have been highly involved in the development of continuous processes for pharmaceutical manufacturing. This session is focused on the applications of continuous manufacturing for drug product. In this session we invite submissions related to the most recent developments in the following areas: (1) Case studies on process development, mathematical modeling of continuous manufacturing unit operations as well as full manufacturing lines, (2) Development of innovative PAT and advanced process control methodologies, (3) Other technical, manufacturing and regulatory challenges involved in continuous manufacturing.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Pharmaceuticals (15B)

Chair:
Robert F. Meyer
Email: robert_meyer2@merck.com

Co-Chair:
Michael C. Dennis
Email: mike.dennis@abbvie.com


3:15 PM
(400a) Selection Support Methodology Between Batch and Continuous Technologies for Pharmaceutical Tablet Manufacturing Processes
Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao and Hirokazu Sugiyama

3:37 PM
(400b) Development of a Continuous Production Line for Solid Dosage Forms Via Dry Granulation
Isabella Aigner, Stephan Sacher, Julia Kruisz, Michael Martinetz, Patrick R. Wahl and Johannes G. Khinast

3:59 PM
(400c) Considerations in Developing a Control Strategy for Continuous Direct Compression
Donald Kientzler, Aditya Vanarase, Anthony Tantuccio, Kevin Macias, Timothy Stevens, Admassu Abebe, Alexander Schaepman and James Holman

4:21 PM
(400d) Applying Supervisory Process Control Practices to Continuous Pharmaceutical Manufacturing
Niels Nicolaï, Ingmar Nopens, Krist V. Gernaey and Thomas De Beer

5:05 PM