709 Quantitative Approaches to Disease Mechanisms & Therapies

Thursday, November 17, 2016: 12:30 PM - 3:00 PM
Continental 8 (Hilton San Francisco Union Square)
Description:
This session highlights applying conventional – e.g., reaction and transport phenomena – and emerging – e.g., dynamical systems and statistical mechanics – concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Bioengineering (15C)

Chair:
Stacey D. Finley
Email: sfinley@usc.edu

Co-Chair:
Roger Harrison
Email: rharrison@ou.edu


12:30 PM
(709a) Model-Based Identification and Evaluation of Abdominal Aortic Aneurysm Surveillance and Surgery Strategies on the Population Level
Farid Heidarnejad and Eric Sherer

12:48 PM
(709b) Model-Based Novel Strategy for Individualized Treatment of Sickle Cell Disease with Hydroxyurea
Akancha Pandey, Robert Hannemann, Terry Vik, Doraiswami Ramkrishna and Sangtae Kim

1:06 PM
(709c) Broadly Neutralizing Antibodies Enhance Clearance of HIV-Infected Cells In Vivo: Pharmacodynamic Analysis of Viral Load Kinetics with Validation in Humanized Mice
Dariusz K. Murakowski, Ching-Lan Lu, Arup K. Chakraborty and Michel C. Nussenzweig

1:24 PM
(709d) Computational Methods at the Intersection of Tuberculosis Immunology and Therapy
Elsje Pienaar, Denise E. Kirschner and Jennifer J. Linderman

1:42 PM
(709e) Cell Population-Based Mathematical Model of Liver Homeostatic Renewal
Daniel Cook, Babatunde A. Ogunnaike and Rajanikanth Vadigepalli

2:00 PM
(709f) Quantitative Dissection of Bacterial Nitric Oxide Stress Networks
Mark Brynildsen

2:18 PM
(709g) Informing the Structural Model of the Mammalian Voltage-Gated Sodium Ion Channel: Probing Protein Conformational Dynamics Using Small-Molecule Neurotoxins
Robert A. Craig II and Justin Du Bois

2:36 PM
(709h) Computational Modeling of Amyloid Aggregation Kinetics
Aditi Sharma, Yury O. Chernoff, Sven H. Behrens and Andreas S. Bommarius
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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