660 Protein Engineering I: Combinatorial Techniques

Thursday, November 17, 2016: 8:30 AM - 11:00 AM
Continental 7 (Hilton San Francisco Union Square)
Description:
The focus of this session will be on the evaluation and implementation of new combinatorial techniques for protein engineering. This includes combinatorial library design, combinatorial library synthesis, high throughput screening/selection techniques, and other novel protein engineering methods. Emphasis will be placed on new techniques or the implementation of existing techniques to address new challenges. Theoretical and experimental work, or a combination thereof, will be considered.

Sponsor:
Bioengineering

Chair:
Benjamin J. Hackel
Email: hackel@umn.edu

Co-Chair:
Amy Karlsson
Email: ajkarl@umd.edu


8:30 AM
(660a) Surface Display-Enabled Directed Evolution of Stabilized Alpha Helix Peptides
Tejas Navaratna and Greg Thurber

8:48 AM
(660b) Fitness Landscapes for an Enzymes on Multiple Substrates
Emily E. Wrenbeck and Tim Whitehead

9:06 AM
(660c) High-Throughput Screening of Biological H2 Production
Jamin Koo, Tim Schnabel, Sylvie Liong, Niklaus Evitt and James R. Swartz

9:24 AM
(660d) Combinatorial Pairwise Assembly Efficiently Generates High Affinity Binders and Enables a “Mix-and-Read” Detection Scheme
Kevin Carlin, Carlos Cruz-Teran, Jay Prakash Kumar, Catherina Gomes and Balaji Rao

9:42 AM
(660e) Affinity-Enhancing Mutations in Different Antibody Complementarity-Determining Regions Display Unique Affinity/Stability Trade-Offs
Mark Julian, Kathryn Tiller, Lilia Rabia and Peter Tessier

10:00 AM
(660f) Evolution of Antibody Agonists That Functionally Recapitulate Natural Cytokines
Jamie B. Spangler, Ignacio Moraga and K. Christopher Garcia

10:18 AM
(660g) New Approaches for High-Throughput Analysis and Engineering of Enzymes and Protein Therapeutics (Featured Presentation)
Jennifer R. Cochran
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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