87 Gene Regulation Engineering

Monday, November 14, 2016: 8:00 AM - 10:30 AM
Continental 9 (Hilton San Francisco Union Square)
The regulation of gene expression dictates virtually all cellular processes with broad applications in biotechnology, medicine and synthetic biology. Controlling these processes requires a detailed understanding of the underlying gene regulatory mechanisms as well as approaches to manipulate existing or engineered regulatory interactions. For this session, we invite high-quality presentations that improve our ability to understand, predict, and control all aspects of gene expression through the quantitative characterization of its many molecular interactions. In addition, presentations on the construction and application of gene regulatory systems will be considered. Potential topics include regulation of transcription, translation, RNA stability, RNA processing, and post-translational modification as well as work that combines multiple gene regulatory systems to generate engineered genetic networks. Presentations that address gene regulation in industrial and medically relevant organisms particularly are encouraged.


Jose L. Avalos
Email: javalos@princeton.edu

Ryan Summers
Email: rmsummers@eng.ua.edu

8:00 AM
(87a) ­Engineering Novel Modular Biosensors to Confer Metabolite-Responsive Regulation of Transcription
Andrew K.D. Younger, Neil C. Dalvie, Peter Su, Austin Rottinghaus and Joshua N. Leonard

8:36 AM
(87c) Orthogonal Regulation of Human Genes Using Chemically Induced Crispr/Cas9 Activators
Zehua Bao, Surbhi Jain, Valerie Jaroenpuntaruk and Huimin Zhao

9:12 AM
(87e) Properties of Intragenic microRNA-Based Gene Regulation in Single Cells and Population Measurements
Kristina Ehrhardt, Neha Kashyap, James Lee, Yi Li, Michael Q. Zhang, Abhyudai Singh and Leonidas Bleris

9:30 AM
(87f) Rational Modular Engineering of a Global RNA Regulator for Tunable Metabolic Control
Abigail N. Leistra, Paul Amador, Arijit Bhuyan and Lydia M. Contreras
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division