69 Biomolecular Engineering

Monday, November 14, 2016: 8:00 AM - 10:30 AM
Continental 8 (Hilton San Francisco Union Square)
Description:
This session invites contributions on novel methods for engineering biomolecules and the applications of these in therapeutics, diagnostics, sensors, and other engineering applications. Novel in vitro and in vivo molecular engineering approaches are also encouraged. Fundamental experimental and computational studies on the structure and structure-function properties of engineered biomolecules are also welcome.

Sponsor:
Engineering Fundamentals in Life Science

Chair:
Lydia Contreras
Email: lcontrer@che.utexas.edu

Co-Chair:
Bradley C. Bundy
Email: bundy@byu.edu


8:00 AM
(69a) A Single Amino Acid Change Confers a Radical Change in the Structure of a Virus-like Particle
Emily Hartman, Michael Asensio, Norma Morella, Jeff Glasgow, Christopher Jakobson, Banumathi Sankaran, Peter H. Zwart and Danielle Tullman-Ercek

8:18 AM
(69b) A Novel Model for the Osmotic Behaviour of Human Mesenchymal Stem Cells
Elisa Casula, Sarah Fadda, Oleksiy V. Klymenko, Cleo Kontoravdi and Alberto Cincotti

8:36 AM
(69c) Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Protein-Ligand Association
Jerome M. Fox, Kyungtae Kang, Madhavi Sastry, Woody Sherman, Banumathi Sankaran, Peter H. Zwart and George M. Whitesides

8:54 AM
(69d) Mitochondrial Metabolism in the Regulation of Human Mesenchymal Stem Cell Immunomodulatory Property
Yijun Liu and Teng Ma

9:12 AM
(69e) Engineering Artificial Metabolons for Substrate Channeling
Kristen E. Garcia, Beyza Bulutoglu and Scott Banta

9:30 AM
(69f) Design and Evaluation of Engineered Protein Biosensors for Live Cell Imaging of Epidermal Growth Factor Receptor Phosphorylation
Shoeb Ahmed, Karthik Tiruthani, Jason Haugh and Balaji Rao

9:48 AM
(69g) Exploiting Structural Effects of Post-Transcriptional RNA Modifications to Engineer Orthogonality of Amber Suppressor Transfer RNAs for Genetic Code Expansion
Kevin C. Baldridge, Andre C. Maranhao, Emmalie Berkovsky, Anirudh Sivakumar, Andrew D. Ellington and Lydia M. Contreras

10:06 AM
(69h) Hybrid Soluble/Cellular Target Selection Schemes Improve Discovery of Translatable Ligands
Lawrence A. Stern, Daniel Woldring and Benjamin J. Hackel
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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