269 Advances in Protein Expression and Post-Translational Modification Platforms

Tuesday, November 15, 2016: 8:30 AM - 11:00 AM
Continental 7 (Hilton San Francisco Union Square)
Description:
This session will highlight advances in protein expression coupled with post-translational protein modification in a wide variety of model and non-model platforms including bacteria, yeast, insect, mammalian, and plant cells as well as cell-free expression systems. Potential topics include but are not limited to glycosylation, lipidation, phosphorylation, nitrosylation, proteolysis, synthesis of spatially organized or scaffolded protein complexes, studies of protein biogenesis, protein folding, and the design of novel methods for protein display, editing and secretion, as well as advances in chemical biology that take advantage of post-translational modification techniques. Presentations that focus on both natural and unnatural post-translational processes that enable enhanced function, stability, or specificity of the protein of interest are particularly welcome.

Sponsor:
Bioengineering

Chair:
Kang Wu
Email: kang.wu@unh.edu

Co-Chair:
Derek Englert
Email: derek.englert@uky.edu


8:48 AM
(269b) Engineering the Type III Secretion Apparatus for Increased Protein Export
Lisa Burdette, Kevin J. Metcalf, Anum Azam, Elias Valdivia and Danielle Tullman-Ercek

9:24 AM
(269d) The Effect of N-Glycosylation on Biophysical Properties of an Anthrax Toxin Bioscavenger
Kalimuthu Karuppanan, Sifti Duhra-Gill, Yongao Xiong, John K. Muchena, My L. Phu, Carlito Lebrilla, Abhaya M. Dandekar, Somen Nandi, Raymond Rodriguez and Karen A. McDonald

9:42 AM
(269e) Glyco-Engineering of CHO Cells for Improved Protein Quality
Ningning Xu, Jianfa Ou, Chao Ma, Ursula L. Triantafillu and Margaret Liu

10:00 AM
(269f) Agrobacterium Mediated Transient Expression of Butyrylcholinesterase, a Biodefense Agent, in Nicotiana Benthamiana Plants
Salem Alkanaimsh, Kalimuthu Karuppanan, Somen Nandi, Raymond Rodriguez and Karen A. McDonald
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division