384 Tools for Accelerating Pharma Development and Innovations in Biopharmaceutical Discovery, Development, and Manufacturing

Tuesday, November 15, 2016: 12:30 PM - 3:00 PM
Continental 5 (Hilton San Francisco Union Square)
Description:
This session is focused on the tools and innovations for accelerating Pharma/BioPharma Discovery, Development and Manufacturing processes. This session will cover computational, in-line/at-line process analytical, and any other innovative tools that enabled fast and robust pharmaceutical processes as well as the new and emerging technology platforms for solids and biologic drugs. This session will also cover the challenges and the strategies to overcome those challenges for process development and scale-up/manufacturing of the drug products.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Separations Division (02), Pharmaceuticals (15B)

Chair:
Preetanshu Pandey
Email: preetanshu.pandey@bms.com

Co-Chair:
Kathleen Mihlbachler
Email: mihlbachler@yahoo.com


12:30 PM
(384a) Use of Real-Time Analytics and Apoptosis Assays for Enhanced Understanding of Cell Growth and Viability in a CHO-Based Process for Monoclonal Antibody Production
Yongqi Wu, Nobel Vale, Vivian Deng, Mina Chaudhry, Dimuthu A. Jayawickrama, Timothy Stevens and Frank Ritacco

12:52 PM
(384b) Providing a Molecular Basis to Modeling Protein Adsorption to Multimodal Carbohydrate-Based Ligands
Shishir PS Chundawat, Sonia K Brady, Vibha Narayanan and Matthew J. Lang

1:14 PM
(384c) Operational Control Strategy Development Via First Principles Mapping
Darrell Staggs and Matthew Foster

1:36 PM
(384d) Nanoextrusion: A Platform Enabling Comparative Assessment of Nanocomposites Vs. Amorphous Solid Dispersions for Drug Dissolution Enhancement
Ecevit Bilgili, Meng Li, Nicolas Ioannidis, Indiana Suriel and Costas G. Gogos

1:58 PM
(384e) Evaporation of Binary Mixtures and Shell Formation in Spray Dried Droplets
Pedro Valente, Íris Duarte, Tiago Porfirio, Xu Liu, Feng Zhang and Márcio Temtem

2:20 PM
(384f) Impact of Tooling Design during Development and Risk Evaluation of Tri-Layer Tablet Formulations
Sophia Robertson-Lavalle, Jing Tao, Preetanshu Pandey and Sherif Badawy

2:42 PM
(384g) End-Point Determination and Scale-up/Scale-Down of High Shear Wet Granulation Process Using an in-Line Di-Electric Probe
Mehrdad Kheiripour Langroudi, Jennifer Sun and W. Mark Eickhoff
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
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