233 Poster Session: Pharmaceutical

Monday, November 14, 2016: 3:15 PM - 5:45 PM
Grand Ballroom B (Hilton San Francisco Union Square)
Poster Session: Pharmaceutical

Pharmaceutical Discovery, Development and Manufacturing Forum
Pharmaceuticals (15B)

Jacob Albrecht
Email: jacob.albrecht@bms.com

Zoltan K. Nagy
Email: znagy@purdue.edu

(233aa) Real-Time Monitoring and Ejection of out-of-Spec Tablets Via NIR Chemical Imaging
Patrick R. Wahl, Gregor Hauseder, Stephan Sacher, Matthias Kerschhaggl and Johannes G. Khinast

(233ab) Solid-State Reactivity of Drugs with Potential Reactive Excipient Impurities: In silico and Experimental Studies
Corinna Gressl, Michael Brunsteiner, Adrian L. Davis, Margaret Landis, Klimentina Pencheva, Garry Scrivens, Gregory Sluggett, Geoffrey Wood, Johannes G. Khinast and Amrit Paudel

(233ac) Comparing and Contrasting the Solid-State Esterification of APIs with Excipient: Computational and Experimental Assessment
Corinna Gressl, Michael Brunsteiner, Adrian L. Davis, Margaret Landis, Klimentina Pencheva, Garry Scrivens, Gregory Sluggett, Geoffrey Wood, Johannes G. Khinast and Amrit Paudel

(233af) The Effect of Particle Engineering on the Processing and the in Vitro Performance of Inhalation Blends in Dry Powder Inhalers
Eva Faulhammer, Sarah Zellnitz, Thomas Wutscher, Johannes G. Khinast and Amrit Paudel

(233ag) Characterization of Compaction Behaviour of Powders in Solid-Dosage Manufacturing Using Finite Element Analysis
Ashish Kumar, Jens Dhondt, Johny Bertels, Didier Klingeleers, Krist V. Gernaey, Ingmar Nopens and Thomas De Beer

(233al) The Effects of Formulation Factors on the Aerosolization Performance of Metered Dose Inhalers
Denise S. Conti, Jay Holt, Poonam Sheth, Dennis Sandell, Anthony Hickey and Bhawana Saluja

(233am) Modeling and Simulation Efforts in Scale up of Sustained Release Microspheres
Rishi Mehan, SVB Janardhan Garikipati, Birendra K. David, Yash Partani and RaviChandra Palaparthi

(233ap) Prediction of Formulation Effects of Continuously Formulated Solid Oral Dosage Forms on Bioavailability Using PBPK Modeling
Clara Hartmanshenn, Patrick J. Sinko, Marianthi G. Ierapetritou and Ioannis P. Androulakis

(233aq) Gender-Dependent PBPK Modeling
Ioannis P. Androulakis, Megerle Scherholz, Patrick J. Sinko, Marianthi Ierapetritou and Clara Hartmanshenn

(233as) Screening a Library of Commercially Available Compounds for Drugs with Novel Anti-Biofilm Activity
Anand Ramasubramanian, Jose Lopez-Ribot, Kai Leung, Anand Srinivasan, Johnathan Abercrombie and Nelson Torres

(233au) Powder Tester Comparison to Predict Discharge Rate from Hoppers and Filling Tablet Press Dies
Joerg Theuerkauf, Yi Fan, Andrew Horton, Madhusudhan Kodam and Karl Jacob

(233aw) Feasibility Analysis of Flowsheet Models in Continuous Pharmaceutical Manufacturing Processes Considering the Effects of Noise
Zilong Wang, M. Sebastian Escotet-Espinoza, Ravendra Singh, Fernando J. Muzzio and Marianthi G. Ierapetritou

(233ax) Process Innovation and Optimization of a Commercial Cell Culture Process
Sivaprakash Agastin, Simpson Gregoire, Sivashankar Sivakollundu and Jeffrey Savard

(233az) Dissolvable Microcarriers for Efficient Cell Production and Recovery
Yue Zhou, Jennifer L. Weber, Kathleen Krebs, Martial Hervy, Marylene Pecheul, Corinne Walerack, David Henry, Marie-Maud Bear and Stephen Caracci

(233e) Computational Fluid Dynamics (CFD) Guided Scale up of Cell Culture Bioreactors from Bench to Pilot to Commercial Scale
William Tran, Garima Chaudhary, Jan-Erik Schaefer, Erik Hasenfus, Thomas Wucherpfennig, Daniel Bock and Henry Lin

(233f) Developing Process Models of Hydrogen Peroxide Decontamination in Pharmaceutical Manufacturing
Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao and Hirokazu Sugiyama

(233g) Modelling Approaches to Spray Drying Process Development, Scale-up and Troubleshooting
Pedro Valente, Íris Duarte, Filipe Neves and Márcio Temtem

(233h) A Comprehensive Statistics-Based Approach to Proactive Process Analysis Including Multivariate Analysis Methods
Sara Koynov, Paige Adack, Conor McCurdy, Orlaith Crowther, Michelle Cleary, Anthony Ruane, Dearbhla Carr, Eoin O'Brien and Jennifer Sun

(233i) Design of Nonlinear Observer for State Estimation of a Bioreactor
Xinghua Pan, Tejasvi Jaladi, Jonathan Raftery, Melanie DeSessa and M. Nazmul Karim

(233l) Model-Based Process Analysis in Continuous Manufacturing of Pharmaceuticals: Calibration of a Fluid Bed Dryer Model
Michael Ghijs, Fien De Leersnyder, Daan Van Hauwermeiren, Valérie Vanhoorne, Jurgen Vercruysse, Philippe Cappuyns, Séverine T.F.C. Mortier, Thomas De Beer, Krist V. Gernaey and Ingmar Nopens

(233n) Fault-Tolerant Control Design and Risk MAP Based Resiliency Analysis of Continuous Solid Dose Manufacturing
Qinglin Su, Mariana Moreno, Sudarshan Ganesh, Arun Giridhar, Gintaras Reklaitis and Zoltan K. Nagy

(233p) Development of a Model Predictive Tool for Continuous Manufacturing of Solid Oral Dosage Forms Via Roller Compaction
Barbara Schaller, Pishnamazi Mahboubah, Patrick Cronin, Ahmad Ziaee, Ahmad Albadarin, Denise Croker, Maurice Collins and Gavin Walker

(233q) Application of Model-Predictive Control to a Feeding Blending Unit
Jakob Rehrl, Julia Kruisz, Stephan Sacher, Martin Horn, Johannes G. Khinast and Isabella Aigner

(233r) Behaviour of Magnesium Stearate in Continuous Feeding
Raghu V. G. Peddapatla, Caroline A. Blackshields, Michael F. Cronin and Abina Crean

(233s) Process Development for Continuous Extrusion and Pelletization of a Heat and Shear-Sensitive Formulation
Theresa R. Hörmann, Gerold Koscher, Stephan Laske and Johannes G. Khinast

(233t) Continuous Manufacturing of Co-Crystals in Twin Screw Extruder: A Case Study
Shaza Darwish, Rahamatullah Shaikh, Manuel Kuhs, Denise Croker and Gavin Walker

(233u) Continuous Wet Granulation in a Twin Screw Extruder: Effect of Process Variables on Residence Time Distribution and Granule Characteristics
Shaza Darwish, Manuel Kuhs, Saeed Shirazian, Jacek Zeglinski, Ahmad Albadarin, Denise Croker and Gavin Walker

Fundamental Modeling and Multivariate Analysis

Continuous Processing

Process Analytic Technology

Material Science

Green Processing

Drug Delivery


Drug Discovery

Pharmaceutical Manufacturing