20 Biomaterials for Nucleic Acid Delivery

Sunday, November 13, 2016: 3:30 PM - 6:00 PM
Golden Gate 3 (Hilton San Francisco Union Square)
Description:
This session will cover novel design principles that govern biomaterial design and evaluation for nucleic delivery applications with particular focus on how biomaterial properties (e.g. mechanical properties, chemical composition, degradation kinetics, micro/nano-structure, etc.) influence the delivery efficiency. Possible topics include, but are not limited to design of novel vehicles for nucleic acid delivery, stimuli-sensitive or targeted delivery, enhancement of delivery/transfection efficiency via specific biomaterial properties and the influence of biomaterial properties on intracellular trafficking and/or transport of nucleic acids. Graduate Students: By applying to this session you may be eligible for the Biomaterials Graduate Student Award Session established to honor the best graduate student submissions through recognition and cash awards. See the session titled “Biomaterials: Graduate Student Award Session” for details.

Sponsor:
Biomaterials
Co-Sponsor(s):
Engineering Fundamentals in Life Science (15D), Bionanotechnology (22B)

Chair:
John Wilson
Email: john.t.wilson@vanderbilt.edu

Co-Chair:
Kaushal Rege
Email: krege@asu.edu


4:06 PM
(20b) Role of SNP Characteristics on the Endocytosis and Intracellular Trafficking of siRNA
Daniel Vocelle, Olivia Chesniak, Mitch Smith, S. Patrick Walton and Christina Chan

4:24 PM

4:42 PM
(20d) Polypeptide/Nucleic Acid Complexes As Delivery Vehicles
Lorraine F. Leon, Cheng-Hsiang Kuo, Myung-Jin Oh, Eun Ji Chung, Yun Fang and Matthew V. Tirrell

5:00 PM
(20e) Highly Potent mRNA Delivery In Vivo with Intravenously-Administered Ionizable Lipid Nanoparticles
Kevin J. Kauffman, Owen S. Fenton, J. Robert Dorkin, Jung H. Yang and Daniel G. Anderson

5:18 PM
(20f) Folate Receptor-Targeted Aminoglycoside-Derived Polymers for Transgene Expression in Cancer Cells
Sudhakar Godeshala, Rajeshwar Nitiyanandan, Brian Thompson, Sheba Goklany, David R. Nielsen and Kaushal Rege
See more of this Group/Topical: Materials Engineering and Sciences Division