341 Computational Methods in Biological and Biomedical Systems

Tuesday, November 15, 2016: 12:30 PM - 3:00 PM
Carmel I (Hotel Nikko San Francisco)
Description:
Biological approaches in chemical engineering are increasingly characterized by systems-level treatment of biological systems and the use of synthetic systems under complex control. Issues such as network size, network cross-talk, and parameter sloppiness can cause significant problems in both numerical analyses and biological interpretation that must be addressed. This session invites contributions that apply existing numerical methods to systems biology and biomedical simulation problems, as well as contributions that identify unique numerical problems that arise in such biological and biomedical systems and address them with novel approaches.

Sponsor:
Applied Mathematics and Numerical Analysis
Co-Sponsor(s):
Engineering Fundamentals in Life Science (15D), Systems and Process Control (10B)

Chair:
Stacey D. Finley
Email: sfinley@usc.edu

Co-chairs:
Ashlee N. Ford Versypt
Email: ashleefv@okstate.edu

Zuyi (Jacky) Huang
Email: zuyi.huang@villanova.edu


12:30 PM
(341a) Identifying Circadian Drug Targets for Maintained Oscillatory Precision
John H. Abel and Francis J Doyle III

12:48 PM
(341b) A Systems-Biology Approach to Investigate the Antimicrobial Activity of Oleuropein
Xianhua Li, Yanhong Liu, Qian Jia, Virginia LaMacchia, Kathryn O'Donoghue and Zuyi (Jacky) Huang

1:06 PM
(341c) VEGFR1 Mediates Cell Migration through Activation of PI3K and PLCɣ
Jared Weddell and Princess Imoukhuede

1:24 PM
(341d) Developing a Stochastic Model of LPS-Induced TNF-α Production in Macrophages
Dongheon Lee, Yufang Ding, Arul Jayaraman and Joseph Sangil Kwon

1:42 PM
(341e) Parameter Estimation for Sparse Biological Data: Glucose-Dependence of Renin-Angiotensin System in Podocytes Cells during Diabetic Kidney Disease
Minu R. Pilvankar, Michele A. Higgins and Ashlee N. Ford Versypt

2:00 PM
(341f) A Method for Learning a Sparse Classification Model in the Presence of Missing Data
Kristen Severson, Brinda Monian, J. Christopher Love and Richard D. Braatz

2:18 PM
(341g) Optimal Experiment Design for Uncertain Biological Systems
Marc Martin-Casas and Ali Mesbah

2:36 PM
(341h) Data-Driven Parameter Reduction in Sloppy Models
Alexander Holiday, Antonios Zagaris, William E. Leeb, William Gear and I.G. Kevrekidis
See more of this Group/Topical: Computing and Systems Technology Division
<< Previous Session | Next Session >>