470016 Power Numbers and Power Correlations for a Retreat-Blade Impeller Under Different Baffling Conditions
In this study the power, P, dissipated by a retreat-blade impeller in different fluids of different viscosities at different agitation speeds and the non-dimensional Power Number, Po, were obtained experimentally in a scaled-down version of a typical glass-lined reactor for pharmaceutical API synthesis. Additionally, P and Po were obtained for an unbaffled system and a fully baffled system (four rectangular baffles) and for a large range of the Reynolds Number (1<Re<1,000,000). Po was found to vary significantly with baffling type and Re.
Equations correlating Po with Re and baffling type were obtained. These equations can be used by industrial users to help quantify and optimize pharmaceutical mixing processes typically involving the synthesis of APIs in this type of reactors.