466307 High Efficient 3D Cell Preservation and Retrieval with Biocompatible Magnetic Hydrogel Particles
In this work, we present a novel strategy for high efficient cell preservation and retrieval at physiological temperature or even room temperature. We proved that biocompatible magnetic hydrogel microparticles could assemble into a 3D environment mimicking ECM for cell accommodation. The cells stay in the interspaces among the hydrogel particles and are supported physically. In this circumstance, cells stop their proliferation while stay alive. Before use, the cells can be easily retrieved by applying an external magnetic field to remove the particles. This strategy can be highly useful for applications such as cell transportaion, in situ diagnostics, drug screening, etc.
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