664 Protein Engineering I: Combinatorial Techniques

Thursday, November 12, 2015: 8:30 AM - 11:00 AM
151A/B (Salt Palace Convention Center)

Description:
The focus of this session is to reflect the latest advances in combinatorial and experimental techniques in protein engineering. Suggested topics include, but are not limited to, (1) development of high throughput screen/selection for protein engineering, (2) development of novel protein engineering methods, (3) protein engineering via directed evolution, and (4) successful application of protein engineering methods to solve new/interesting problems.

Sponsor:
Bioengineering
Chair:
James A. Van Deventer Email: jvandev@mit.edu
Co-Chair:
Xin Ge Email: xge@engr.ucr.edu


8:30 AM
(664a) Tuning Phage Display and Yeast Surface Display for Panning for Novel Ligands on Tumor Cells
Lawrence A. Stern, Ian A. Schrack, Aakash Deshpande, Sadie M. Johnson and Benjamin J. Hackel


8:50 AM
(664b) Stabilization of Xylanase By Its Random Insertional Fusion to a Thermophilic Host Protein Domain
Vandan Shah, Brennal Pierre, Tamari Kirtadze, Seung Shin and Jin Ryoun Kim


9:10 AM
(664c) Co-Evolution of Affinity and Stability of Alzheimer's Domain Antibodies Using Yeast Surface Display
Mark C. Julian, Christine C. Lee, Kathryn E. Tiller, Lilia A. Rabia and Peter M. Tessier


9:30 AM
Break


9:50 AM
(664e) The Distribution of Fitness Effects of Indels in TEM-1 Beta-Lactamase
Courtney Gonzalez, Paul Roberts and Marc Ostermeier


10:10 AM
(664f) Protein Engineering As a Tool to Improve the Surfactant Activity of OmpA Protein from Escherichia coli
Vanessa Lucia Nuñez Velez, Silvia Restrepo Restrepo, Oscar Alberto Alvarez and Andres Fernando González Barrios


10:30 AM
(664g) Directed Evolution of Self-Cleaving Intein Purification Tags with Improved Cleavage Kinetics
Samuel D. Stimple, Michael J. Coolbaugh, Yamin Fan, Kyle Cochran and David W. Wood
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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