534 Fundamentals of Protein Folding in Diseases

Wednesday, November 11, 2015: 12:30 PM - 3:00 PM
151A/B (Salt Palace Convention Center)

Description:
This session seeks submissions focused on experimental and theoretical characterization and prediction of the thermodynamics and mechanism(s) of protein folding as well as the role that aggregates play in disease pathogenesis. Areas of interest include, but are not limited to, the dynamics and mechanisms of protein aggregation, the formation of off-pathway aggregates, the characterization of aggregate size and structure, the therapeutic inhibition of aggregation, and the interaction of aggregates with target cells.

Sponsor:
Bioengineering
Chair:
Melissa Moss Email: mossme@engr.sc.edu
Co-Chair:
Jin Ryoun Kim Email: jkim@poly.edu
- indicates paper has an Extended Abstract file available on the online proceeding.



(534a) Hofmeister Effects on Aggregation and Prion Strain Generation By Amyloid Beta 1-42
Aditi Sharma, Sven H. Behrens, Yury O. Chernoff and Andreas Bommarius


(534b) Quercetin and Metabolites Reduce Amyloidß-Induced Apoptosis Associated with Alzheimer's Disease
Kayla Pate, McCall Rogers, Nicholas van der Munnik and Melissa Moss

File available
(534c) Cystatin C: A Cerebrospinal Fluid Protein with Both Amyloid and Anti-Amyloid Activity
Tyler Perlenfein and Regina M. Murphy


(622b) Transport of Amyloid-ß Across the Blood Brain Barrier By P-Glycoprotein (Rapid Fire)
Hope Holt, Elizabeth Moore, Melissa Moss, Fransico Gonzalez and Melissa Moss


(620z) Soy isoflavones target amyloid-β oligomers associated with Alzheimer’s disease (Rapid Fire)
S. Zeb Vance, Colman Moore, Kayla Pate and Melissa Moss


(620ac) Microcalorimetry Applied to the Study of Protein Stability (Rapid Fire)
Link Brown and Kristina Lilova


(620ay) Dynamics of Aggregation of Proteins (Rapid Fire)
Size Zheng, Katherine S. Shing and Muhammad Sahimi


(620bb) Oligomer Formation of Toxic and Functional Amyloid Peptides Studied with Atomistic Simulations (Rapid Fire)
Martin Carballo Pacheco, Ahmed E. Ismail and Birgit Strodel


(534d) A New Class of Compounds Inhibiting the Amyloidosis of TTR(105-115): Insights from Experiments and Molecular Dynamics Simulations
Phanourios Tamamis, Nicos Christophi, Panayiota Pepi, Andrey A. Berezin, Georgia A. Zissimou, Andrew J Palughi, Panayiotis A. Koutentis and Sophia C. Hayes


(534e) Effect of Oscillating Electric Field on Preformed Human Serum Albumin Fibrils
Shubhatam Sen, Monojit Chakraborty, Snigdha Goley, Swagata Dasgupta and Sunando DasGupta


(534f) The Fragmentation of Amyloid Fibrils Occurs in Preferential Positions Depending on the Environmental Conditions
Lucrece Nicoud, Stefano Lazzari, Daniel Barragan and Massimo Morbidelli
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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