570 Advances in Protein Expression and Post-Translational Modification Platforms

Wednesday, November 11, 2015: 3:15 PM - 5:45 PM
151A/B (Salt Palace Convention Center)

This session will highlight advances in protein expression coupled with post-translational protein modification in a wide variety of model and non-model platforms including bacteria, yeast, insect, mammalian, and plant cells as well as cell-free expression systems. Potential topics include but are not limited to glycosylation, lipidation, phosphorylation, nitrosylation, proteolysis, synthesis of spatially organized or scaffolded protein complexes, studies of protein biogenesis, protein folding, and the design of novel methods for protein display, editing and secretion, as well as advances in chemical biology that take advantage of post-translational modification techniques. Presentations that focus on both natural and unnatural post-translational processes that enable enhanced function, stability, or specificity of the protein of interest are particularly welcome.

Tamara L. Kinzer-Ursem Email: tursem@purdue.edu
Bradley C. Bundy Email: bundy@byu.edu

3:15 PM
(570a) Refolding of Heterologous Proteins in the Extracellular Space after Secretion
Kevin James Metcalf, Sandy Rosales, Anum Azam, Elias Valdivia and Danielle Tullman-Ercek

3:51 PM
(570c) The Potential of Small Molecules to Modulate Glycosylation By Media Design
David Brühlmann, Anais Muhr, Jürgen Hemberger, Markus Sauer, Henri Kornmann, Martin Jordan and Hervé Broly

4:09 PM

4:27 PM
(570e) Engineered Ca2+-Binding Protein for Chemoenzymatic Tagging and Bioorthogonal Surface Conjugation
Chethana Kulkarni, Megan Lo, Julia G. Fraseur, David A. Tirrell and Tamara L. Kinzer-Ursem

4:45 PM
(570f) Post-Translational Azide Functionalization for Optimizing Immobilized Protein Properties
Joseph Plaks, Rebecca Falatach, Jason A. Berberich and Joel L. Kaar

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division