686 Crystallization of Pharmaceutical and Biological Molecules I

Thursday, November 12, 2015: 12:30 PM - 3:00 PM
Ballroom D (Salt Palace Convention Center)

Description:
This session welcomes papers addressing fundamental as well as applied studies in the area of crystallization of pharmaceutical or biological molecules. Topics related to experimental studies, theory and simulation that contribute to fundamental understanding of crystallization as well as industrial case studies on the crystallization development of pharmaceutical and biological compounds are encouraged.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Crystallization and Evaporation (02B), Pharmaceuticals (15B)
Chair:
Ryan C. Snyder Email: rcs048@bucknell.edu
Co-chairs:
Zoltan K. Nagy Email: zknagy@purdue.edu
Moiz Diwan Email: moiz.diwan@abbvie.com


12:30 PM
Introductory Remarks


12:35 PM
(686a) Molecular Mobility As a Tool for Understanding the Impact of Polyvinylpyrrolidone (polymer) and Tpgs (surfactant) in Crystallization Kinetics of Amorphous Celecoxib
Darlene Santiago, Lynne Taylor and Laura Mosquera


12:55 PM
(686b) Process Development for a Co-Crystal of Telaprevir (VX-950) and 4-Hydroxybenzoic Acid
Billie Kline, Todd Blythe, Eric Borsje, Eleni Dokou, Rahela Gasparac, Michael L Hurrey, Megna Israni, Meghan Johnston, Valdas Jurkauskas, Dragutin Knezic, Praveen Mudunuri, Yolanda Pesha, Kareem Reda, Brian Phenix and Charles Van Kirk


1:15 PM
(686c) Primary Nucleation Under High Shear Conditions
Moiz Diwan, Huayu Li and Fredrik Nordstrom


1:35 PM
(686d) Microfluidic Spherical Crystallization and Co-Formulation of Drugs and Excipients – Controlling Morphology and Polymorphism
Eunice Wan Qi Yeap, Ambika Somasundar, Denise Zi Ling Ng, Yiji Wang and Saif A. Khan


1:55 PM
(686e) Morphology Evolution of Quadrangular Dendrites of Erythritol
Ting Wang, Jingkang Wang and Hongxun Hao
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
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