416 Nanotechnology in Medicine and Drug Delivery

Tuesday, November 10, 2015: 3:15 PM - 5:45 PM
Ballroom B (Salt Palace Convention Center)

Description:
Nanotechnology is gaining an increasing interest and application in the pharmaceutical industry. In particular nanoparticles and nanocarriers can help overcome shortcomings related to insufficient water solubility, low dissolution rate and poor permeability. Additional benefits of nanocarriers include target delivery to specific locations in the gastrointestinal tract, enhanced permeability via transcytosis and enhanced delivery of macromolecules. Further, nanocarriers provide a much enhanced target specificity over traditional drug delivery means which represents a great hope for improving chemotherapy treatment. This session will focus on recent advances in synthesis and engineering of nanomaterials for enhanced drug delivery and patient treatment and the development of their manufacturing processes.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum
Co-Sponsor(s):
Pharmaceuticals (15B)
Chair:
Lotfi Derdour Email: lotfi.x.derdour@gsk.com
Co-chairs:
Bei Chen Email: bei.chen@abbvie.com
Celia N. Cruz Email: Celia.Cruz@fda.hhs.gov


3:15 PM
(416a) Design of Dendrimer-Doxorubicin Conjugates for Transport Modulation Across in Vitro Pulmonary Epithelium and Their Solution Formulation in Pressurized-Metered Dose Inhalers
Qian Zhong, Bruno Humia, Alisha Punjabi and Sandro R. P. da Rocha


3:40 PM
(416b) Controlling Mechanical Properties and Dissolution Rate of Strip Films Loaded with Griseofulvin Nanoparticles
Scott M. Krull, Hardik Patel, Meng Li, Ecevit Bilgili and Rajesh N. Dave


4:05 PM
(416c) Lipid-Polymeric Hybrid Nanoparticle Based Nicotine Vaccine: Size Matters
Zongmin Zhao, Yun Hu, Reece Hoerle, Meaghan Devine and Chenming Zhang


4:30 PM
(416d) High Throughput Synthesis of Nanovaccine Formulations
Jonathan Goodman, Lucas Dunshee, Akash Mitra and Balaji Narasimhan


4:55 PM
(416e) Preparation and Characterization of Pegylated, Acid-Labile Dendrimer-Doxorubicin Conjugates and Their Aerosol Formulation in Propellant-Based Inhalers
Qian Zhong and Sandro R. P. da Rocha


5:20 PM
(416f) A Drug-Sparing Approach to the Preparation of Drug Nanosuspensions: High-Intensity Vibratory Milling
Ecevit Bilgili, Lu Zhang, Meng Li and Rajesh N. Dave
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
<< Previous Session | Next Session >>