707 Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond

Thursday, November 12, 2015: 12:30 PM - 3:00 PM
155D (Salt Palace Convention Center)

Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Crystallization and Evaporation
Jason Sweeney Email: jason.sweeney@bms.com
Zoltan K. Nagy Email: zknagy@purdue.edu
- indicates paper has an Extended Abstract file available on CD.

12:35 PM
(707a) Microfluidic Platform for Cocrystal Screening and Characterization
Elizabeth M. Horstman, Yuchuan Gong, Geoff G. Z. Zhang and Paul J. A. Kenis

12:55 PM
(707b) Identification and Crystallization Development of Potential Conformational Polymorphs of an Active Pharmaceutical Ingredient
Bing-Shiou Yang, Joe Gao, Zhibin Li, Michelle Raikes, Thomas Offerdahl, John Smoliga, Jane Li, Rogelio Frutos, Xiaorong He and Keith Horspool

1:15 PM
(707c) Depiction and Prediction of Practical Pathways for Crystallization
Christopher Viney, Stephen Watt and Jason Komadina

1:55 PM

2:15 PM
See more of this Group/Topical: Separations Division