681 Biomaterials for Nucleic Acid Delivery

Thursday, November 12, 2015: 12:30 PM - 3:00 PM
251A (Salt Palace Convention Center)

Description:
This session will cover novel design principles that govern biomaterial selection for gene delivery applications with particular focus on how biomaterial properties (e.g. mechanical properties, chemical composition, degradation kinetics, micro/nano-structure, etc.) influence the delivery efficiency. Possible topics include, but are not limited to stimuli-sensitive or targeted delivery, enhancement of delivery/transfection efficiency via specific biomaterial properties and the influence of biomaterial properties on intracellular trafficking and/or transport of nucleic acids.

Sponsor:
Biomaterials
Chair:
Angela K. Pannier Email: apannier2@unl.edu
Co-Chair:
Kaushal Rege Email: krege@asu.edu
- indicates paper has an Extended Abstract file available on CD.


File available
12:30 PM
(681a) Design of Biodegradable Polycations for Localized Gene Delivery from Layer-By-Layer Coatings
Lingxiao Xie, Maria Muniz and Guangzhao Mao


12:48 PM
(681b) siRNA-Loaded Lipidoid Nanoparticles for the Treatment of Mantle Cell Lymphoma
Christopher Knapp and Kathryn A. Whitehead


1:06 PM
(681c) The Role of Nanotopography on Cellular Responsiveness to Nonviral Gene Delivery
Amy Mantz, Tadas Kasputis, Eva Schubert, Mathias Schubert and Angela K. Pannier


1:24 PM
(681d) Light-Induced Gene Silencing for Applications in Regenerative Medicine
Millicent O. Sullivan, Chad T. Greco and Thomas H. Epps III


1:42 PM
(681e) Engineering Delivery Vehicles for siRNA Therapeutics
Daniel Vocelle, Olivia Chesniak, Mitch Smith, Christina Chan and S. Patrick Walton


2:00 PM
(681f) Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
Rebecca Ball, Christopher Knapp and Kathryn A. Whitehead


2:18 PM
(681g) Engineering pH-Responsive Nanoparticles for Delivery of Immunostimulatory Nucleic Acids to Cytosolic Immune Surveillance Pathways
Max Jacobson, Kathryn Bumila, Sema Sevimli and John Wilson


2:36 PM
(681h) Collagen Mimetic Peptides for Integration of Gene Delivery with Tissue Repair
Millicent O. Sullivan, Morgan A. Urello and Kristi L. Kiick
See more of this Group/Topical: Materials Engineering and Sciences Division
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