Abstract: Sulfur-containing heterocyclic compounds are frequently found in naturally occurring compounds and generally show various biological activities. Benzo[d]imidazo[2,1-b]thiazole is an important chemical building block in synthetic organic and biological chemistry. A facile, efficient, and simple protocol for the synthesis of benzo[d]imidazo[2,1-b]thiazole through copper-catalyzed aerobic oxidative cyclization between 2-aminobenzothiazole and ketone has been developed. The reaction proceeds smoothly to furnish the products in atom economy. A variety of fused benzoimidazothiazole derivatives were synthesized with satisfactory yields.
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 Mishra, S.; Monir, K.; Mitra, S.; Hajra, A. Org. Lett. 2014, 16, 6084- 6087
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