467 Protein Engineering III: Therapeutics

Wednesday, November 19, 2014: 8:30 AM
205 (Hilton Atlanta)
Description:
This session will focus on protein engineering for therapeutic applications, with an emphasis on emerging topics and recent successes. Potential areas of interest include, but are not limited to, engineered antibodies for cell targeting and imaging, antibodies involved in disease pathologies, and advances in antibody therapeutics.

Sponsor:
Bioengineering

Chair:
Xin Ge
Email: xge@engr.ucr.edu

Co-chairs:
Laura Segatori
Email: segatori@rice.edu

Danielle Tullman-Ercek
Email: dtercek@berkeley.edu

Tamara L. Kinzer-Ursem
Email: tursem@purdue.edu


8:30 AM
(467a) Synergy and Stability in the Treatment of Pertussis: Bispecific Antibody Vs Binary Mixture?
Ellen K Wagner and Jennifer A Maynard

8:48 AM
(467b) Optimized or-Gate Chimeric Antigen Receptor for Adoptive T-Cell Therapy Against B-Cell Malignancies
Eugenia Zah, Anne Silva, Michael Jensen and Yvonne Chen

9:06 AM
(467c) Targeting Cystathionine-Gamma-Lyase to the Tumor Vasculature in Enzyme Prodrug Therapy of Breast Cancer in an Immune-Competent Mouse Model
John Krais, Carla Kurkjian and Roger Harrison

9:24 AM
(467d) Advancing Next-Generation Sequencing Based Methods for Antibody Discovery and Engineering
Sai T. Reddy

9:42 AM
Break

9:48 AM
(467e) A Conformation-Switching Protein Probe for Detection of Alpha Synuclein Oligomers
Michael Hernandez, Yang Hu and Jin Ryoun Kim

10:06 AM
(467f) Evolving a 45-Amino Acid Ligand Scaffold for Enhanced Stability and Tumor Targeting
Max A Kruziki, Andrew Easton and Benjamin J. Hackel

10:24 AM
(467g) Imaging Agent Design for Type 1 Diabetes
Liang Zhang and Greg Thurber

10:42 AM
(467h) Engineering Exosomes As Therapeutic Delivery Vehicles
Michelle E. Marcus and Joshua N. Leonard
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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