347 Protein Engineering II: Rational and Computational Techniques

Tuesday, November 18, 2014: 12:30 PM
205 (Hilton Atlanta)
Description:
This session will focus on techniques for computational and rational design approaches to protein engineering, including, but not limited to, (1) advances in rational protein engineering techniques, (2) advances in computational protein engineering techniques, and (3) hybrid computational and experimental techniques for improved protein engineering approaches. Submissions combining computationally/rationally inspired libraries with experimental screening are especially encouraged.

Sponsor:
Bioengineering

Chair:
Amy J. Karlsson
Email: ajkarl@umd.edu

Co-Chair:
Tim Whitehead
Email: taw@msu.edu

- indicates paper has an Extended Abstract file available on CD.


12:30 PM
(347a) Computational Characterization of Effects of Mutations on the Allosteric Communication Pathways of Hsp70
André A. S. T. Ribeiro and Vanessa Ortiz

12:48 PM
(347b) From HIV-1 gp120 V3 Loop Binding to CXCR4 / CCR5, to De Novo Design of a Dual Targeted CXCR4 / CCR5 Anti HIV-1 Peptide
Phanourios Tamamis, James Smadbeck and Christodoulos A. Floudas

1:06 PM
(347c) Molecular Dynamics Simulation of Plantaricin E/F, a Class IIb Bacteriocin
Panagiota Kyriakou and Yiannis N. Kaznessis
File available
1:24 PM
(347d) Optmaven: De Novo Design of Antibody Variable Regions
Tong Li, Robert J. Pantazes and Costas D. Maranas

1:42 PM
Break

1:48 PM
(347e) Computational Design of Peptides That Bind to the Boxb RNA with High Affinity
Xingqing Xiao, Michelle E. Marcus, Joshua N. Leonard and Carol K. Hall

2:06 PM
(347f) Protid: Systematic Identification of Protein Scaffolds for Molecular Recognition
Patrick Holec, Max A Kruziki, Dan Beech and Benjamin J. Hackel

2:24 PM
(347g) Design and Evolution of Domain Antibodies Specific for Amyloid Proteins
Kathryn E. Tiller, Mark C. Julian, Fanling Meng, Christine C. Lee, Lilia A. Rabia, Benjamin M. Richardson, Evan K. Day, Sarah E. DuCogne, Esther C. Maeng and Peter M. Tessier

2:42 PM
(347h) Controlling Local Substrate Concentrations and Enzyme Kinetics through Rationally Designed Intermolecular Interactions
Yingning Gao, Christopher C. Roberts, Jie Zhu, Jyun-Liang Lin, Chia-en Chang and Ian Wheeldon
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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