173 Cell Culture III: Metabolic Flux Analysis and Modeling

Monday, November 17, 2014: 3:15 PM
206 (Hilton Atlanta)
This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, therapeutics and high-value secondary metabolites. This session will focus on phenotype characterization using metabolic flux analysis and metabolomics, and the development of mathematical models towards prediction and control of cell culture behavior on small and large scales.


Vijay Janakiraman
Email: vijay.janakiraman@biogenidec.com

Maciek R. Antoniewicz
Email: mranton@udel.edu

3:15 PM
(173a) 13C-Metaboloic Flux Analysis of Microbial Cell Factories: A Touch of Revelation
Lian He, Arul Varman, Whitney Hollinshead, Gang Wu, Haifeng Hang and Yinjie J. Tang

3:51 PM
(173c) Lactate's Impact on Breast Cancer Metabolism
Arthur Nathan Brodsky, Dan Odenwelder and Sarah W. Harcum

4:09 PM
(173d) 13C Flux Analysis of Metabolic Phenotypes Associated with Apoptotic Resistance in CHO Cells
Allison McAtee, Neil Templeton, Abasha Lewis, Kevin Smith, Michael J. Betenbaugh and Jamey D. Young

4:27 PM

4:51 PM
(173f) Understanding the Effect of Mild Hypothermia on Monoclonal Antibody Glycosylation through Flux Balance Analysis and Mechanistic Modelling
SI Nga Sou, Christopher Sellick, Ken Lee, Alison Mason, Sarantos Kyriakopoulos, Karen M. Polizzi and Cleo Kontoravdi
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division