282 Quantitative Approaches to Disease Mechanisms & Therapies

Tuesday, November 18, 2014: 8:30 AM
201 (Hilton Atlanta)
This session highlights applying conventional e.g., reaction and transport phenomena and emerging e.g., dynamical systems and statistical mechanics concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Engineering Fundamentals in Life Science
Systems and Process Control (10B), Applied Mathematics and Numerical Analysis (10D)

Matthew J. Lazzara
Email: mlazzara@seas.upenn.edu

Stacey Finley
Email: sfinley@usc.edu

9:06 AM

9:24 AM
(282d) Elucidating Mechanisms of Liver Metastasis: An All-Human Microphysiological Model to Investigate Disease Progression & Therapies
Carissa L. Young, Sarah E. Wheeler, Amanda M. Clark, Donna B Stolz, Alan Wells, Linda G. Griffith and Douglas Lauffenburger

10:00 AM
(282f) Impact of Necrotizing Enterocolitis on the Barrier Properties of Intestinal Mucus
Taylor Carlson, Hasan M. Yildiz, Erika Claud and Rebecca L. Carrier

10:18 AM
(282g) Human Metabolic Response to Systemic Inflammation: Concordance Between the Experimental Endotoxemia and Clinical Cases
Kubra Kamisoglu, Steve E. Calvano, Susette M. Coyle, Siobhan A. Corbett and Ioannis P. Androulakis

10:36 AM
(282h) The Effects of Fluid Shear Stress on Cancer Stem Cells
Ursula L. Triantafillu, Ria C. Domier, David A. Dozier and Yonghyun (John) Kim
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division