580 Multivariate Analysis in Support of Development or Manufacture of Medicines

Wednesday, November 19, 2014: 3:15 PM
202 (Hilton Atlanta)
Description:
This session welcomes papers on the application of multivariate statistics in process development and drug manufacture. Topics include, but are not limited to, control of process and product quality, optimization of process parameters and design of experiments, model calibration, signal processing, and method development across a wide range of drug substance and drug product applications. Contributions from both industry and academia are encouraged.

Sponsor:
Pharmaceutical Discovery, Development and Manufacturing Forum

Chair:
James C. Marek
Email: james.marek@abbvie.com

Co-Chair:
Jason Sweeney
Email: jason.sweeney@bms.com


3:15 PM
(580a) Wavenumber Selection for NIR Calibration Modeling: Application to Water and Drug Content Estimation
Taku Uchimaru, Takuya Miyano, Koichi Fujiwara, Manabu Kano, Hideaki Tanabe, Hiroshi Nakagawa, Tomoyuki Watanabe and Naoki Wakiyama

3:40 PM
(580b) Improvement of Iterative Optimization Technology (Calibration-Free/ Minimum Approach) with Dimensionality Reduction of Spectra
Hiromasa Kaneko, Koji Muteki, Daniel O. Blackwood, Yang A. Liu, Sonja Sekulic and Kimito Funatsu

4:05 PM
(580c) Application of Multivariate Data Analysis to Cell Culture Development
John Bowers

4:30 PM
(580d) Model Development for NIR-Based Real-Time Monitoring of Ingredient Concentration
Hiroshi Nakagawa, Manabu Kano, Shinji Hasebe, Takuya Miyano, Tomoyuki Watanabe and Naoki Wakiyama

4:55 PM
(580e) Detection of Process Fingerprints Applying Multivariate Analysis Methods to Monoclonal Antibody Cell Culture Data
Michael Sokolov, Alessandro Butté, Miroslav Soos and Massimo Morbidelli
See more of this Group/Topical: Pharmaceutical Discovery, Development and Manufacturing Forum
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