280 Protein Engineering I: Combinatorial Techniques

Tuesday, November 18, 2014: 8:30 AM
205 (Hilton Atlanta)
Description:
The focus of this session is to reflect the latest advances in combinatorial and experimental techniques in protein engineering. Suggested topics include, but are not limited to, (1) development of high throughput screen/selection for protein engineering, (2) development of novel protein engineering methods, (3) protein engineering via directed evolution, and (4) successful application of protein engineering methods to solve new/interesting problems.

Sponsor:
Bioengineering

Chair:
Mark A. Blenner
Email: blenner@clemson.edu

Co-Chair:
Thomas J. Mansell
Email: thomas.mansell@colorado.edu


8:30 AM
(280a) Protein Engineering of β-Lactam Antibiotics-Producing Enzymes: α-Amino Acid Ester Hydrolase and Cocaine Esterase
Marietou F. Paye and Andreas S. Bommarius

8:48 AM
(280b) A Streamlined Protein Purification Platform for Toxic Proteins Based on Intein Trans-Splicing
Changhua Shi, Miriam Shakalli Tang and David W. Wood

9:06 AM
(280c) Enhancing Biomolecular Screening By Combining Yeast Surface Display with Noncanonical Amino Acids
James A. Van Deventer, Ryan L. Kelly, Doris N. Le, Jessie Zhao and K. Dane Wittrup

9:24 AM
Break

9:42 AM
Break

9:48 AM
(280e) Extending the Utility of the Amine Dehydrogenase: Increased Affinity and Synthesis of (S)-Amine
Samantha Au, Bettina Bommarius, Michael J. Abrahamson, Martin Schürmann and Andreas S. Bommarius

10:06 AM
(280f) Intracellular FRET-Based Assay for Redesigning the Specificity of Secreted Proteases
Jennifer Guerrero, Michelle A. O'Malley and Patrick S. Daugherty

10:24 AM
(280g) Sequence-Function Mapping of Full-Length Protein Sequences
Caitlin A. Kowalsky and Tim Whitehead

10:42 AM
(280h) Optimizing Combinatorial Diversity with High Throughput Selections and Computation
Daniel Woldring, ShengShee Thor, Patrick Holec and Benjamin J. Hackel
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
<< Previous Session | Next Session >>