52 Cell Culture I: Process and Media Design

Monday, November 17, 2014: 8:30 AM
206 (Hilton Atlanta)
Description:
This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, pharmaceuticals, vaccines and high-value secondary metabolites. Topics for this session focus on experimental methods which include, but are not limited to bioreactor design, media development, and improvement of product yield or quality through process optimization, process characterization and control.

Sponsor:
Bioengineering

Chair:
Jeremiah Zartman
Email: zartman.3@nd.edu

Co-Chair:
Jamey D. Young
Email: j.d.young@vanderbilt.edu


8:30 AM
(52a) Continuous MINI-Reactors for CELL Culture Applications: Examples of Biopharmaceutical and Biomedical Applications
Grissel Trujillo-de Santiago, Roberto Portillo-Lara, Sandra Ozuna Chacón, Felipe López-Pacheco, María del Rosario Rocha-Pizaña, Julián López-Meza, Ernesto Di Maio and Mario M. Alvarez

8:48 AM
(52b) Product Quality Control of Monoclonal Antibodies By Integrated Continuous Manufacturing
Daniel Karst, Fabian Steinebach, Monica Angarita, Elisa Serra, Massimo Morbidelli and Miroslav Soos

9:06 AM
(52c) Modeling and Modulating N-Linked Glycosylation – Differences and Similarities in Fed-Batch and Continuous Cultures
Thomas K. Villiger, Ernesto Scibona, Massimo Morbidelli and Miroslav Soos

9:24 AM
(52d) Differences in Recombinant Monoclonal Antibody Glycosylation Between Stable and Transient Gene Expression Systems
SI Nga Sou, Christopher Sellick, Ken Lee, Alison Mason, Karen M. Polizzi and Cleo Kontoravdi

9:42 AM
Break

9:48 AM
(52e) Effect of Media Supplements on the Glycosylation Profile in MAbs
Devesh Radhakrishnan, Anne S. Robinson and Babatunde A. Ogunnaike

10:06 AM
(52f) Continuous Production of Monoclonal Antibodies in Attached CHO CELL Culture MINI-Reactors: Use of Zein Foams As a Matrix for CELL Adhesion
Grissel trujillo De Santiago, Sandra Ozuna Chacón, Julián López-Meza, Felipe López-Pacheco, María del Rosario Rocha-Pizaña, Diana Aráiz-Hernández, Salvatore Iannace, Ernesto Di Maio and Mario M. Alvarez

10:24 AM
(52g) Time-Dependent Stress and Multipotency Response of Glioma to Low Oxygen Tension in Vitro
David A. Dozier, Samantha G. Tilson and Yonghyun (John) Kim

10:42 AM
(52h) Scale-up of the Production of Rotavirus on Sp2/0-Ag14 Cell Culture up to 2L Bioreactor
Eliana Lozano-Romero, Ruben Godoy-Silva and Carlos Arturo Guerrero
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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