46 Bioseparations and Downstream Processing

Monday, November 17, 2014: 8:30 AM
205 (Hilton Atlanta)
Description:
This session will focus on highlighting the latest advances in downstream processing relevant to purification/polishing operations including rapid process development, improved efficiency, cost reduction, integration of operations, handling of high titre streams and sustainability issues. Topics to be covered include, but are not limited to: Uni- and multi-modal chromatography, membrane-based separations and filtration, extraction, precipitation and crystallization.

Sponsor:
Bioengineering

Chair:
Caryn L. Heldt
Email: heldt@mtu.edu

Co-Chair:
Todd J. Menkhaus
Email: Todd.Menkhaus@sdsmt.edu


8:30 AM
(46a) Affinity Chromatography of IgG Based on Octapeptide Ligands Designed By Biomimetic Method
Weiwei Zhao, Fufeng Liu, Qinghong Shi, Xiaoyan Dong and Yan Sun

8:48 AM
(46b) Rational Design and Engineering of Peptides for Affinity Purification of Biologics
Divya Chandra, Steve Timmick, Divya Shastry, Chaz Goodwine, J. P. Trasatti, James A. Woo, Steven M. Cramer and Pankaj Karande

9:06 AM
(46c) Control of Intein-Mediated Recombinant Protein Purification
Tzu-Chiang Han and David W. Wood

9:24 AM
(46d) Reducing Host Cell Burden By Strategic Genome Design
Bob Beitle, Ellen M. Brune, McKinzie Fruchtl, Mohammad M. Ataai and Ralph Henry

9:42 AM
Break

9:48 AM
(46e) Lectin-Mediated Affinity Precipitation Affords High-Yield Recovery of Fucosylated Proteins from Plant Crude Extract
Lindsay Arnold

10:06 AM
(46f) Purification of Plant-Made Human Recombinant Alpha-1-Antitrypsin
Kalimuthu Karuppanan, Salem Alkanaimsh and Karen A McDonald

10:24 AM
(46g) Virus Flocculation and Removal in the Presence of Osmolytes
Maria F. Gencoglu and Caryn L. Heldt

10:42 AM
(46h) Strategy to Control Aggregate Levels in an Fc-Fusion Protein Purification Process
Christopher L. Thompson, Ellen O'Connor and Alan K. Hunter
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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