46 Bioseparations and Downstream Processing

Monday, November 17, 2014: 8:30 AM
205 (Hilton Atlanta)
This session will focus on highlighting the latest advances in downstream processing relevant to purification/polishing operations including rapid process development, improved efficiency, cost reduction, integration of operations, handling of high titre streams and sustainability issues. Topics to be covered include, but are not limited to: Uni- and multi-modal chromatography, membrane-based separations and filtration, extraction, precipitation and crystallization.


Caryn L. Heldt
Email: heldt@mtu.edu

Todd J. Menkhaus
Email: Todd.Menkhaus@sdsmt.edu

8:30 AM
(46a) Affinity Chromatography of IgG Based on Octapeptide Ligands Designed By Biomimetic Method
Weiwei Zhao, Fufeng Liu, Qinghong Shi, Xiaoyan Dong and Yan Sun

8:48 AM
(46b) Rational Design and Engineering of Peptides for Affinity Purification of Biologics
Divya Chandra, Steve Timmick, Divya Shastry, Chaz Goodwine, J. P. Trasatti, James A. Woo, Steven M. Cramer and Pankaj Karande

9:24 AM
(46d) Reducing Host Cell Burden By Strategic Genome Design
Bob Beitle, Ellen M. Brune, McKinzie Fruchtl, Mohammad M. Ataai and Ralph Henry

9:42 AM

10:06 AM
(46f) Purification of Plant-Made Human Recombinant Alpha-1-Antitrypsin
Kalimuthu Karuppanan, Salem Alkanaimsh and Karen A McDonald

10:24 AM

10:42 AM
(46h) Strategy to Control Aggregate Levels in an Fc-Fusion Protein Purification Process
Christopher L. Thompson, Ellen O'Connor and Alan K. Hunter
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division