724 Engineered Composite Particulate Systems for Pharmaceutical Active Ingredient Delivery

Thursday, November 20, 2014: 3:15 PM
209 (Hilton Atlanta)
Description:
The main objective of this session is to encourage papers and subsequent discussions that lead to development of the scientific foundation for forming building blocks such as particles, suspensions, granules, etc, consisting of pharmaceutical active ingredients with desired properties that improve the final product quality. Presentations dealing with development of science-based methodologies, processes, and formulations for forming materials engineered to have desired properties required for achieving ideal active substance delivery are encouraged. Major topics, include but are not limited to; formation and stabilization of particle suspensions, novel formulations to improve bioavailability of APIs, methods for particle functionalization and surface modification for optimizing and controlling physicochemical properties of materials that impact composite particle system performance.

Sponsor:
Particle Production and Characterization

Chair:
Stephen L. Conway
Email: stephen_conway@merck.com

Co-Chair:
Rajesh Dave
Email: dave@njit.edu

- indicates paper has an Extended Abstract file available on CD.


3:15 PM
(724a) Inhalable Nanocomposites for Targeted Pulmonary Delivery and Applications in Lung Cancer Therapy
Nathanael A. Stocke, Heidi M. Mansour, Meenakshi Upreti, Susanne Arnold and J. Zach Hilt

4:06 PM
(724d) Engineering Fine Crystalline API Via High Shear Direct Precipitation with Isolation Using a Thin Film Evaporator
Luke Schenck, Michael Toth, Tiffany Chiang, Piaget Francois, Joe Kukura and Aaron Cote

4:23 PM
(724e) Transition from Spray Drying to Hot Melt Extrusion with Affinisol™ HPMC HME
William Porter III, Kevin O'Donnell, Wes Spaulding and Uma Shrestha
See more of this Group/Topical: Particle Technology Forum