654 Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond

Thursday, November 20, 2014: 8:30 AM
301 (Hilton Atlanta)
Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Crystallization and Evaporation

Marina Tsianou
Email: mtsianou@buffalo.edu

8:30 AM

9:12 AM
(654b) Predicting the Neat Polymorphs of Axitinib
Manolis Vasileiadis, Constantinos C. Pantelides and Claire S. Adjiman

9:56 AM
(654d) Prediction of Energetic Energetic Cocrystal Forms and Their Competition with Solvate Formation
Andreas Klamt, Christoph Loschen, David am Ende and Stephen R. Anderson

10:18 AM
(654e) Nucleation and Growth of Organic Semiconductor Polymorphs
Ying Diao, Kristina Lenn, Paulette Clancy, Zhenan Bao and Stefan Mannsfeld
See more of this Group/Topical: Separations Division