376993 A Biofabrication Approach for Controlled Synthesis of Silver Nanoparticles with High Catalytic and Antibacterial Activities

Tuesday, November 18, 2014
Galleria Exhibit Hall (Hilton Atlanta)
Cuixian Yang, Sukwon Jung and Hyunmin Yi, Department of Chemical and Biological Engineering, Tufts University, Medford, MA

Simple, facile and size-controllable synthesis of uniform Ag nanoparticles with tobacco mosaic virus (TMV) as a biomediator was developed in the absence of external reducing agents. Ag nanoparticles with average diameter of 2, 4 and 9 nm were obtained by simply tuning the ratio of TMV/Ag(NH3)2+. Autocatalytic growth followed by coalescence was observed from Ag formation in the presence of TMV.  The as-prepared TMV-mediated Ag nanoparticles show substantially higher catalytic and antibacterial activities than previous results. For the 4-nitrophenol hydrogenation reaction, the rate constants per surface area for 2 and 9 nm Ag nanoparticles were determined to be 0.64 and 1.2 L m−2 s−1 respectively. Both Kirby–Bauer disk diffusion test and tube culture results demonstrate high antibacterial activity of TMV-mediated Ag particles against Escherichia coli, with minimal inhibition concentration (MIC) of 2.3 and 2.5 ppm for 2 and 9 nm Ag nanoparticles respectively. We expect that our biomediated Ag synthesis approach can be readily extended to other biomaterials and metal nanoparticle systems.

Extended Abstract: File Not Uploaded
See more of this Session: Poster Session: Nanoscale Science and Engineering
See more of this Group/Topical: Nanoscale Science and Engineering Forum