448 Quantitative Approaches to Disease Mechanisms & Therapies

Wednesday, November 6, 2013: 8:30 AM
Golden Gate 2 (Hilton)
Description:
This session highlights applying conventional – e.g., reaction and transport phenomena – and emerging – e.g., dynamical systems and statistical mechanics – concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Systems and Process Control (10B)

Chair:
Heather Fahlenkamp
Email: heather.fahlenkamp@okstate.edu

Co-Chair:
Antonios Armaou
Email: armaou@psu.edu

- indicates paper has an Extended Abstract file available on CD.


8:30 AM
(448a) Using An Agent-Based Model of Mycobacterium Tuberculosis Infection to Understand the Roles of Interleukin-10 During Disease Progression
Nicholas A. Cilfone, Denise E. Kirschner and Jennifer J. Linderman

8:48 AM
(448b) Vessel Wall Transport: Can Increasing the Endothelial Cell Expression of the Membrane Protein Aquaporin-1 Slow Down Pre-Lesion Atherosclerosis?
Shripad D. Joshi, Chirag B. Raval, Kung-Ming Jan and David S. Rumschitzki

9:06 AM
(448c) Platelet Count Control in Immune Thrombocytopenic Purpura Patient: Optimum Romiplostim Dose Profile
Chia-Hung Tsai, Stanley I. Sandler and Babatunde A. Ogunnaike

9:24 AM
(448d) Design of a Drug Infusion Controller for Reducing Post-Operative High Blood Pressure
Sarah Mailhiot, Maureen Newman, Nicolina DiNardi, Katherine Maziarski, Elexis Baral, Taha Hasekioglu and Juergen Hahn

9:42 AM
(448e) Model-Based Identification of Therapeutic Intervention Targets in Calcium-Related Pathologies
Christopher R. Christie, Luke E. K. Achenie and Babatunde A. Ogunnaike
File available
10:00 AM
(448f) Cardiac Alternans Annihilation By Optimal and Model Predictive Control
Felicia Yapari and Stevan Dubljevic

10:18 AM
(448g) Autocatalytic Release of Heme in Sickle and Normal Erythrocytes
Anupam Aich, Melissa Freundlich, Elena V. Petrova, Ye Li, Bogdan Dinu, Gladstone Airewele and Peter G. Vekilov

10:36 AM
(448h) Biofilm Mitigation Via Magnetic Hyperthermia
Ann O'Toole and Eric Nuxoll
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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