451 Solid Form Selection: Cocrystals, Salts, Solvates, Polymorphs, and Beyond

Wednesday, November 6, 2013: 8:30 AM
Union Square 1 (Hilton)
Continuous improvement of the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, dissolution rate, stability, hygroscopicity, crystallinity and taste, represents an emerging area of research and development. This session focuses on the selection of solid forms including cocrystals, salts, solvates and polymorphs in crystallization processes, as well as the screening, predicting, manipulating and controlling techniques for such product selection.

Crystallization and Evaporation

Fang Wang
Email: fang.wang@gilead.com

- indicates paper has an Extended Abstract file available on CD.

File available
9:10 AM
(451c) Polymorph Prediction: A Kinetic Approach
Meenesh R. Singh, Conor Parks, Hsien-Hsin Tung, Shailendra Bordawekar and Doraiswami Ramkrishna

9:50 AM
(451e) Application of Microfluidics in the Solid Form Screening of Pharmaceutical Parent Compounds
Sachit Goyal, Elizabeth Horstman, Aristotle Economou, Garam Lee, Yuchuan Gong, Geoff G.Z. Zhang and Paul J.A. Kenis

10:10 AM
(451f) Form Selection and Methods to Improve the Hygroscopic Behavior of the Selected Form
Bing Shi, Olga Lapina, Peter Fung, Fang Wang, Melissa Casteel, Vahid Zia, Dimitrios Stefanidis, Patricia Macleod and Lister Lam
See more of this Group/Topical: Separations Division