636 Numerical Methods in Synthetic and Systems Biology

Thursday, November 7, 2013: 8:30 AM
Continental 6 (Hilton)
Description:
Biological approaches in chemical engineering are increasingly characterized by systems-level treatment of biological systems and the use of synthetic systems under complex control. Issues such as network size, network cross-talk, and parameter sloppiness can cause significant problems in both numerical analyses and biological interpretation that must be addressed. This session invites contributions that apply existing numerical methods to systems and synthetic biology problems, as well as contributions that identify unique numerical problems that arise in such biological systems and address them with novel approaches.

Sponsor:
Applied Mathematics and Numerical Analysis
Co-Sponsor(s):
Bioengineering (15c)

Chair:
Mark P. Styczynski
Email: Mark.Styczynski@chbe.gatech.edu

Co-Chair:
Roman S. Voronov
Email: rvoronov@seas.upenn.edu

- indicates paper has an Extended Abstract file available on CD.


8:30 AM
(636a) Development and Comparison of Computer-Aided Methods for the Optimal Design of Lyophilized Protein Formulations
Brock C. Roughton, Kyle V. Camarda and Elizabeth M. Topp

8:50 AM
(636b) System Identification and the “Omics” – Challenges in the Time of Big Data
Jason E. Shoemaker, Yoshihiro Kawaoka and Hiroaki Kitano

9:10 AM
(636c) Advanced Modeling of Oral Drug Delivery -- Innovation in Tablet Design
Naresh Pavurala and Luke E. K. Achenie
File available
9:30 AM
(636d) Regulatory T-Cell Differentiation Plasticity Model
David Chaar, Juergen Hahn, Arul Jayaraman, Robert Alaniz and Shelby Steinmeyer
File available
9:50 AM
(636e) Effects of Scaffold Degradation and Geometrical Structure On Vascularization: A Multi-Agent Systems Approach
Hamidreza Mehdizadeh, Elif S. Bayrak, Sami Somo, Eric M. Brey and Ali Cinar

10:10 AM
(636f) Thrombogenesis & Intra-Clot Molecular Transport: Modeling Vs Reality
Roman S. Voronov, John Welsh, Timothy J. Stalker, Lawrence F. Brass and Scott L Diamond

10:30 AM
(636g) Whole-Brain Computational Fluid Dynamic Analysis
Thomas Marrinan and Andreas Linninger
See more of this Group/Topical: Computing and Systems Technology Division
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