509 Quantitative Approaches to Cancer Mechanisms & Therapies

Wednesday, November 6, 2013: 12:30 PM
Golden Gate 2 (Hilton)
Description:
This session highlights applying conventional – e.g., reaction and transport phenomena – and emerging – e.g., dynamical systems and statistical mechanics – concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Biomedical Applications of Chemical Engineering (T7), Systems and Process Control (10B)

Chair:
Shelly R. Peyton
Email: speyton@ecs.umass.edu

Co-Chair:
Robert Parker
Email: rparker@engr.pitt.edu


12:30 PM
(509a) Interstitial Fluid Pressure Modulates Gene Expression in Engineered Models of Breast Tumors
Alexandra Piotrowski, Joe Tien and Celeste M. Nelson

12:48 PM
(509b) Engineered Tissues to Quantify the Biology of Tumor Spread
Lauren E. Barney, Erinn C. Dandley and Shelly R. Peyton

1:06 PM
(509c) Identifying Determinants of EGFR-Targeted Therapeutic Efficacy Using Computational Modeling
Calixte S. Monast and Matthew J. Lazzara

1:24 PM
(509d) An Algorithm for Patient-Specific Cancer Chemotherapy Scheduling
Thang Ho and Robert S. Parker

1:42 PM
(509e) Tumor Derived Exosomes As Local Modulators of Immunogenic Field Effects in Melanoma
Yueting Wu, Emily Chambers and David J. Klinke

2:00 PM
(509f) An Automated System for the Design of Optimal Personalized Chemotherapy Protocols for the Treatment of Leukemia
Eleni Pefani, Nicki Panoskaltsis, Eirini Velliou, Maria Fuentes, Athanasios Mantalaris, Michael C. Georgiadis and Stratos N. Pistikopoulos

2:18 PM
(509g) The Role of Reductive Carboxylation in Warburg-Like Renal Cancer Cells
Paulo A. Gameiro, Ana Metelo, Rocio Perez Carro, Pilar López Larrubia, Othon Iliopoulos and Gregory N. Stephanopoulos
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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