560 Nucleic Acid Delivery

Wednesday, November 6, 2013: 3:15 PM
Golden Gate 2 (Hilton)
Description:
This session seeks to explore topics associated with the development of novel gene delivery vehicles and processes in gene and/or oligonucleotide delivery.

Sponsor:
Engineering Fundamentals in Life Science
Co-Sponsor(s):
Biomedical Applications of Chemical Engineering (T7)

Chair:
Joshua Ramsey
Email: josh.ramsey@okstate.edu

Co-Chair:
Christopher Jewell
Email: cmjewell@umd.edu


3:15 PM
(560a) Polymer-Based Multilayer Coatings for the Rapid Release of DNA From Surfaces: A Weak Polyelectrolyte Approach
Yan Yu, Yi Si, Shane L. Bechler, Bo Liu and David M. Lynn

3:33 PM
(560b) Synergistic Combination of Coated Microneedles and Biochemical Approaches for Oligonucleotide Delivery to Cells in 3D Tissues
Zhen Luo, Ting Ye, Yunzhe Ma, Harvinder S. Gill and Nitin Nitin

3:51 PM
(560c) Cellular and Molecular Factors Contribute to An in Vitro Refractory Period Between Sequential DNA Complex Deliveries
Abby M. Kelly, Timothy M. Martin, Sarah A. Plautz and Angela K. Pannier

4:09 PM
(560d) Acid-Degradable Polyketal Nanoparticles Carrying MnSOD siRNA to Restore Intrinsic Apoptosis in Tamoxifen-Resistant Breast Cancer Cells
Soo Kyung Cho, Jessica A. Kemp, Ali Pedram, Ellis R. Levin and Young Jik Kwon

4:27 PM
(560e) Dendrimer-siRNA Complexes and Their Aerosol Formulation for Lung Delivery Applications
Denise S. Conti, Daniel Brewer, Jordan Grashik, Sumant Avasarala and Sandro R. P. da Rocha

4:45 PM
(560f) Modification of Fiberless Adenovirus With a Polymer/Peptide Conjugate for Enhanced Transduction and Reduced Immune Response
Adane Nigatu, Grit Kupgan and Joshua D. Ramsey

5:03 PM
(560g) In Vivo Evaluation of AAV-Mediated Gene Transfer in Airways of Mice With Acute Or Chronic Respiratory Infection
Melissa Myint, Maria P. Limberis and Scott L. Diamond

5:21 PM
(560h) Directed Evolution of Adeno-Associated Virus for Enhanced Evasion of Human Neutralizing Antibodies
Melissa A. Kotterman, Bum-Yeol Hwang, Daniel Stone, James T. Koerber, Linda Couto, Federico Mingozzi, Katherine High and David V. Schaffer
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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