582 Poster Session: Bioengineering

Wednesday, November 6, 2013: 6:00 PM
Grand Ballroom B (Hilton)
Description:
This poster session presents quantitative bioengineering research projects, both finished and ongoing. This includes, but is not limited to, experimental, theoretical, and computational advances in metabolic engineering, protein engineering, synthetic biology, systems biology, and the bioproduction of renewable fuels, chemicals, and pharmaceuticals as well as bioinformatics, bioreactors, fermentation, cell culture, and downstream processing. We encourage the submission of high quality abstracts that describe quantitatively and specifically the research work to be presented.

Sponsor:
Bioengineering

Chair:
Curt R. Fischer
Email: curt@ginkgobioworks.com

Co-Chair:
Ian R. Wheeldon
Email: iwheeldon@engr.ucr.edu

- indicates paper has an Extended Abstract file available on CD.


(582a) Activation of Plant Anticancer Compounds By the Gut Microbiota
Camil A. C. Diaz, Andrew P. Klein and Elizabeth Sattely

(582aa) Predication of Sialic Acid Reduction in CHO Culture
Nicholas Alden

(582ac) Application of Multivariate Analysis of Metabolic Models for Predictability of Cell Culture Performance and Quality Attributes; An Industry Prospective
Nicole Migliore, Krista Tomlin-Verni, John Cunningham, Steve Mehrman, Mark-John Bruwer, Eugene Schaefer and Marta Abad
File available
(582ad) Using Design of Experiment (DOE) Principles Toward Titer Optimization in Perfusion Cell Culture
Matthew P. Zustiak and Matthew V. Caple

(582af) Rational Approach for the Improvement of Cell Culture Media Based On the Life Cycle Management of An Investigational Product
Sean McDermott, Christopher Racicot, Patrick Hossler and John C.H. Fann

(582ah) Effect of Agitation Rate in Hybridoma Cell Culture On Monoclonal Antibody Production
Yuki Nakajima, Yoichi Kumada and Michimasa Kishimoto

(582ak) Encapsulation of Heterologous Pathways Within the Pdu Microcompartment of Salmonella Enterica
Marilyn F. Slininger and Danielle Tullman-Ercek

(582al) Supercooling: A Viable Non-Freezing Preservation Method of Hepatocytes
O. Berk Usta, Yeonhee Kim, Sinan Ozer, Bote Bruinsma, Jungwoo Lee, Esin Demir, Tim Berendsen, Catheleyne Puts, Maria-Louisa Izamis, Korkut Uygun, Basak Uygun and Martin L. Yarmush

(582am) Constraints-Based Flux Balance Analysis In Cancer Cell Growth and Metabolism
Charudatta Navare, Riya Uthup, Mridula Prasad, Priyanka Sadhukhan and Anu Raghunathan

(582an) Stabilization of a Fiberless Adenovirus Gene Vector
Grit Kupgan, Shyamal Choudhari, Nicholas Flynn, Adane Nigatu, Sravanthi Vupputuri, William Picking, Wendy Picking and Joshua D. Ramsey

(582ao) Enhanced and Sustained Transgene Expression Mediated By a Binary Baculoviral System
Li-Yu Sung and Yu-Chen Hu

(582ap) Use of the Osteopontin Promoter for Expression-Targeted Cancer Gene Therapy
Xuguang Chen and W. T. Godbey

(582as) Multi-Level Optimization Framework for the Identification of Multi-Objective Design Principles in Metabolic Networks
Pavel Vaskan, Gonzalo Guillén-Gosálbez and Laureano Jimenez

(582at) Transgenic Expression of Thermomyces Lanuginosus and Candida Antarctica Lipases in Plants for the Enzymatic Production of Biodiesel
Ye Deng, Michael Gagnon, Subhash Minocha and Palligarnai Vasudevan

(582au) Production of Bifunctional Molecules By Clostridium Sp. BOH3
Gobinath Rajagopalan, Jianzhong He and Yang Kun-Lin

(582aw) Engineering Rhodobacter Sphaeroides for Direct Electron Transfer By Heterogenous Expression of Redox-Active Components From Electrogenic Species
Danhui Cheng, Wanyang Wang, King Lau Chow and I-Ming Hsing
File available
(582ax) Development of Novel Feed Additives Through the Production of Recombinant Proteins in Microalgal Chloroplasts
Gabriel Potvin and Zisheng Zhang

(582ay) HEK 293 Platform Bioprocess Development for Second Generation Programs Leveraging Knowledge From First Generation Processes and An Existing In-House CHO Platform Process
Terrence M. Dobrowsky, Kyle McElearney, Rashmi Kshirsagar and Thomas Ryll

(582az) Antimicrobial Peptides Targeting Gram-Negative Pathogens, Produced and Delivered By Lactic Acid Bacteria
Katherine G. Volzing, Juan Borrero, Michael Sadowsky and Yiannis N. Kaznessis

(582b) Computational Design of New Peptide Inhibitors for Amyloid Beta (Aβ) Aggregation in Alzheimer's Disease: Application of a Novel Methodology
Mert Gur and Gozde Eskici

(582ba) Understanding the Functional Oligomerization State of Peridinin-Chlorophyll a-Proteins in the Dinoflagellate Symbiodinium
Jing Jiang, Hao Zhang, Robert Blankenship and Cynthia S. Lo
File available
(582bb) Efficient Production and Molecular Design of Microbial Surfactants for Next-Generation Biochemicals
Masaaki Konishi, Mizuki Ikarashi, Yuji Hatada, Takahiko Nagahama and Jun-ichi Horiuchi

(582bd) Rational Engineering of the Dxp Pathway for Overproduction of Isoprenoids in Bacteria
Kang Zhou, Ruiyang Zou, Congqiang Zhang, Gregory Stephanopoulos and Heng-Phon Too

(582be) A Systems Approach for Metabolic Engineering of Tryptophan in Escherichia Coli
SelvaRupa Christinal Immanuel, Abhishek Gupta and Anu Raghunathan

(582bf) Effect of Heterogeneous Cultivation Conditions On Mammalian Cell Productivity and Product Quality
Benjamin Neunstoecklin, Maximilian Lularevic, Massimo Morbidelli and Miroslav Soos
File available
(582bg) Engineering Human Paraoxases for Quorum Sensing Quenching
Cathy X Li and Xin Ge

(582bi) High-Throughput Optimization of Genetically Refactored Nitrogenase Gene Clusters
Lauren B. A. Woodruff, Michael J. Smanski, D. Ben Gordon, Robert Nicol and Christopher A. Voigt

(582bj) Human Fc Receptor Fragment Production for Antibody Drugs Purification By Escherichia Coli
Kotaro Iwatani, Seigo Oe, Yoichi Kumada and Michimasa Kishimoto

(582bk) Characterization and Engineering of Acyltransferase Domains in the Pursuit of Novel Polyketide Therapeutics
Briana Dunn

(582bl) Secretory Expression of Laccase From Geobacillus
Tony Castagnaro and Kang Wu

(582bm) Generation of Resveratrol Analogues By Enzymatic Oligomerization and Protein Engineering
Namita Bhan, Mauricio Mora-Pale, Mattheos A.G. Koffas, Robert J. Linhardt, Jonathan S. Dordick and Sayaka Masuko

(582bn) Fermentation of Agrobacterium Tumefaciens for Large-Scale Transient Expression of Recombinant Proteins In Plants
Ingrid Leth and Karen A McDonald

(582bo) Engineering Lipid Droplet Targeting Domains in S.Cerevisiae
Patrick Ho, Jyun-Liang Lin and Ian Wheeldon

(582bp) Metabolic Engineering of Escherichia Coli for the Production of Medically Valuable Polysaccharides
Brady Cress, Robert J. Linhardt and Mattheos A.G. Koffas

(582bq) Toward Microbial Factories: Mechanism and Kinetics of Enzyme Encapsulation in Bacterial Microcompartments
Christopher Jakobson and Danielle Tullman-Ercek

(582br) Engineering Pentose Sugar Fermentation in Zymomonas Mobilis for Efficient Fuel Ethanol Production From Lignocellulosic Feedstocks
Kori Dunn and Christopher V. Rao

(582bs) Frontier Manufacturing: Scaling Up Synthetic Biology
Karen M. Polizzi, Jason P. Hallett, Cleo Kontoravdi and Nilay Shah
File available
(582bt) Isobutyraldehyde Production From Escherichia Coli By Removing Aldehyde Reductase Activity
Gabriel Rodriguez and Shota Atsumi

(582bu) Microbial Production of 2,3 Butanediol and L-Lactate From Seaweed Hydrolysate Using Metabolically Engineered Escherichia Coli
Suman Mazumdar

(582bw) Application of 13C Metabolic Flux Analysis to Understanding the Physiology of Engineered Geobacillus Thermoglucosidasius
Charlotte E. Ward and David J. Leak

(582bx) The Effects of NADPH Reducing Power On Isopropanol Production in Clostridium Tyrobutyricum
Wenyan Jiang and Shang-Tian Yang

(582bz) Rewiring Yeast Sugar Transporter Preference Through Modifying a Conserved Protein Motif
Eric M. Young, Alice Tong and Hal Alper

(582ca) Real-Time Monitoring Of Bacterial Growth and Biofilm Formation With Surface Plasmon Resonance Imaging
Pegah N. Abadian and Edgar D. Goluch

(582cb) Engineering Acetogenic Clostridia for Ethanol and n-Butanol Production From CO2
Chih-Chin Chen and Shang-Tian Yang

(582cd) Analysis of Photomixotrophic Metabolism in Synechocystis Sp. PCC 6803 Via Inverse Tracer-Metabolic Flux Analysis
Le You, Lian He, Bertram M. Berla, Himadri Pakrasi and Yinjie J. Tang

(582ce) Determination of the Metabolic Pathways for Linear Hydrocarbon Biosynthesis in the Green Algae Botryococcus Braunii Strain UTEX572
Mark T. Brown
File available
(582cf) A Flow-Cytometry Method for Optimizing Transformation Conditions in Bacteria
Benjamin Woolston, Hamid Rismani-Yazdi and Greg Stephanopoulos

(582cj) In Silico Metabolic Model of Gordonia Alkanivorans to Study Its Desulfurization Characteristics
Shilpi Aggarwal, Iftekar A. Karimi and Gregorius Ivan
File available
(582ck) Global Alterations in the Secretome of B. Subtilis and S. Cerevisiae
Elizabeth G Frayne

(582co) Wastewater Treatment in Cellulosic Biorefineries Via Bioelectrochemical Systems
Abhijeet P. Borole

(582cp) Design and Technoeconomic Analysis of a Biomanufacturing Facility for Production of a Biodefense Agent
Karen A McDonald, Renner Burkle, Collin Chew, Charley Li, Kevin O'Brien, Kristen Paridon, Tiffany Tu and Josh Wang

(582cq) The Effect of Bark Inclusion On Bioethanol Production in a Spruce-to-Ethanol Process
Balázs Frankó, Ola Wallberg and Mats Galbe

(582cr) Robust Sample Generation and Data Analysis for the Application of Metabolomics in Bioprocessing
Vijay Janakiraman, An Zhang, Rashmi Kshirsagar and Thomas Ryll

(582cs) Sensitive, Rapid, Amplification-Free Immunoassay Using Labeled Bacteriophage, Magnetic Capture Beads and Image Processing Techniques
Jinsu Kim, Meenu Adhikari, Sagar Dhamane, Julia Litvinov, Anna E. V. Hagström, Katerina Kourentzi, Ulrich Strych, Richard C. Willson and Jacinta C. Conrad

(582cv) Functional Role of the Tryptophan Residue On the Transmembrane Domain of the IRE1α Protein
Hyunju Cho, Francesca Stanzione, Amadeu K. Sum and Christina Chan

(582cw) Immobilization of Cellulase On a Silica Gel Substrate Modified Using a 3-Aptes Self-Assembled Monolayer
Dezhi Zhang, Hisham Hegab, Yuri Lvov and James D. Palmer

(582cy) Controllable Depolymerization of Heparin By the Combinations of Heparinases I/II/III for the Production of Low Molecular Weight Heparins
Jingjun Wu, Chong Zhang, Ye Li, Xiang Mei and Xinhui Xing

(582cz) Multiscale Investigation of Biomolecular Systems Dynamics
Mert Gur, Elia Zomot, Jeffry D. Madura and Ivet Bahar
File available
(582d) Selective Recovery From the Interstitial Spaces of Leaves
Nathaniel Kingsbury and Karen A McDonald
File available
(582db) The Uptake of Cu in Tyrosinase Affects the Monophenolase/Diphenolase Activity Ratio
Ayelet Fishman

(582dc) A Novel Protein Structure Refinement Method: Blind Predictions During CASP10, and An Optimized Protocol to Maximize Performance
George A. Khoury, Phanourios Tamamis, Neesha Pinnaduwage, James Smadbeck, Chris A. Kieslich and Christodoulos A. Floudas

(582de) Stabilization of Vaccines in Silk
Jeney Zhang, Bruce Panilaitis and David L Kaplan
File available
(582df) Evaluating a Novel Aquaporin From R. Sphaeroides for Biomimetic Membrane Applications
Mustafa Erbakan, Yue-xiao Shen, Manish Kumar and Wayne R. Curtis

(582dg) Plantseed: Utilizing Functional Annotation of Plant Protein Families to Generate Metabolic Models Capable of Phenotypic Predictions
Sam Seaver and Christopher S. Henry
File available
(582di) Directed Evolution Of Nitrobenzene Dioxygenase For The Production Of The Antioxidant Hydroxytyrosol
Ayelet Fishman

(582dj) Protein Polymerization Technique Using Horseradish Peroxidase Catalyzed Tyorsine Coupling Reaction
Kosuke Minamihata, Teruyuki Nagamune, Masahiro Goto and Noriho Kamiya

(582dk) Engineering 3-Dimensional Protein Scaffolds for Biocatalysts Assembly
Qi Chen, Qing Sun, Szu-Wen Wang and Wilfred Chen
File available
(582dl) Effect of Different Ratio of Air-CO2 Mixing Feed On the Growth of Nannochloropsis Oculata in Batch Photobioreactors
Shaikh Razzak, Muhammad Ilyas and Mohammad M. Hossain

(582dn) A Potent Multi-Cellulase Conjugate System Using a DNA Scaffold to Enhance Cellulose Degradation
Noriho Kamiya, Yutaro Mori, Tsutomu Tanaka and Hirofumi Ichinose

(582do) Development of Binding Domains for Improved Cellulose Decrystallization and Hydrolysis
Yuzhi Kang, Prabuddha Bansal, Bettina Bommarius, Matthew Realff and Andreas S. Bommarius

(582dp) Targeted Chemical Biotinylation of Protein Complexes Using Monomeric Streptavidin
Jasdeep Mann, Daniel DeMonte and Sheldon Park

(582dq) Refolding and Immobilization of Peptide-Tag-Fused VHH Antibodies and Its Application to the Sensitive Immunoassays
Kagenari Yamakawa, Yoichi Kumada and Michimasa Kishimoto

(582dr) A Facile Resolution of (R, S)-Mandelic Acid Via Lipase-Catalyzed Esterification
Liping Tong, Mengfan Wang, Wei Qi, Rongxin Su and Zhimin He

(582du) Evaluation of the Influence of pH and Temperature On Enzymatic Activity of Alfa-Acetolatato Decarboxylase
Celina Maria Lemos, Ítalo Waldimiro Lima França Sr., Ticiane C. Souza and Luciana R. B. Gonçalves
File available
(582dv) Production of Flavor Esters By Candida Antarctica Lipase Type B Immobilized On Magnetic Nanoparticles
Kimberle P. Santos, Marcela Y. Farias, Maria Cristiane Martins de Souza, Rafael Freire, Antonio CESAR H. Barreto, Pierre BasÍlio Fechine and Luciana R. B. Gonçalves

(582dx) Refolding of Laccase With Copper-Based Ionic Liquid
Sang-Woo Bae and Yoon-Mo Koo

(582dz) Positive Inotropy – a Likely Mechanism for Lipid Reversal of Local Anesthetic Toxicity
Belinda S. Akpa
File available
(582e) Expression of Recombinant Human Butyrylcholinesterase in Nicotiana Benthamiana and Its Postproduction In‐vitro Glycosylation Modification
Salem Alkanaimsh, Somen Nandi, Min Sook Hwang, Andrés Guerrero, Yanhong Li, Lucas Arzola, Bryce Hashimoto, Aye Tu, My Phu, Abhaya M. Dandekar, Bryce W. Falk, Xi Chen, Carlito Lebrilla, Raymond Rodriguez and Karen A McDonald

(582eb) E. Coli Derived Substrate Quantifies ADAMTS13 Protease Activity in Blood Plasma Using Flow Cytometry
Shobhit Gogia, Chi Lo and Sriram Neelamegham

(582ec) Engineering a Proteolytically Stable and Biologically Active Fibronectin
Nancy Wangechi Karuri, Chen Zhang and Raj Desai

(582ed) Adsorption Characteristics of Whole Antibody and Scfv Onto Various Plastic Surfaces for Improvement of Sensitivity in ELISA
Ryosuke Miyamoto, Yoichi Kumada and Michimasa Kishimoto

(582ee) Structural and Activity Characterization of Irradiated Antimicrobial Peptide (WLBU2) for Use in Blood Processing and Biomedical Applications
Daniel Cheung, Matthew Ryder and Karl Schilke

(582f) Dynamic Adhesion Assays for Understanding the Significance of CD151 in the Metastatic Cascade
Jennifer Fischer, Adrianne Shearer, Xiuwei Yang, Christine Trinkle, Richard E. Eitel and Kimberly W. Anderson

(582g) Proteome Analysis of Secretome From Thermophilic Lignocellulose Degrading Microbe Geobacillus Sp. WSUCF1
Aditya Bhalla, Nirmal Uppugundla, Bruce Dale, Venkatesh Balan and Rajesh K. Sani
File available
(582h) Production of Biosurfactant By a Microorganism Isolated From a Brazilian Mangrove: Influence of Oxygen Transfer On the Bioreactor
Italo Waldimiro Franca, Joao Alexandre Lemos, Darlane Oliveira Sr., Ticiane Souza, Celina Maria Lemos, Vania Maria M. Melo, Hosiberto B. Sant'ana and Luciana R. B. Gonçalves
File available
(582i) Polymer-Conjugated Enzyme Biohybrid Carriers for Detoxification Processes-Internal Diffusion and Kinetics
Robert Compton, Matthew Eggert, Mark E. Byrne and Robert P. Chambers

(582j) Fitselect: A Synthetic Gene Circuit to Guide Combinatorial Metabolic Engineering Experiments
Benjamin G. Freedman and Ryan S. Senger

(582k) Aggrecan As a Chondroinductive Signal in Interpenetrating Network Hydrogels for Cartilage Tissue Engineering
Deena Rennerfeldt, Stevin H. Gehrke and Michael Detamore

(582l) Mechanical Phenotyping of Tumor Cells Using a Multiplexed Microfluidic Cell Squeezer Device
Nabiollah Kamyabi, Zeina S. Khan and Siva A. Vanapalli

(582m) The Complimentary Use of Sophisticated (SIMS) and Crude (Nile red) Chemical Screening to Improve Algae As a Biofuels Production Platform
Justin Yoo, Lauren Jackson, Ryan Johnson, Benjamin Geveke, Alex Rajangam, Ramya Mohandass, Nicholas Winograd and Wayne R. Curtis

(582n) Quantitative Tailoring of RNA Device Activity for Conditional Control of Cell Fate
Andrew L. Chang

(582o) Soft Immobilization of Redox Mediator for Electroenzymatic Synthesis
Hana Lee, Hye Jung Lee, Sang Hyun Lee, Chan Beum Park and Keehoon Won

(582p) Simulation of Turbulence Effects On Red Blood Cell Trauma
Mesude Ozturk, Edgar A. O'Rear and Dimitrios V. Papavassiliou

(582r) Harnessing Flux Balance Analysis for Simulating Biological Evolution
James D. Winkler and Katy Kao

(582s) Effect of Sodium Chloride On Properties of Thermoplastic Starch/Poly(butylene adipate-co-terephthalate) Blend
Chindawan Punchangcharoen and Amporn Sane

(582t) Droplet-Based Microfluidic Device for Small Animal Drug Screening
Mizanur Rahman, Zeina S. Khan, Frank V. Bussel, Nathaniel Szewczyk, Jerzy Blawzdziewicz and Siva A. Vanapalli
File available
(582u) Small Reaction Volume Trend to Produce Monodisperse Gold Nanoparticles in the Biosynthesis By Bacteria
Hao Lv, Jinsheng Sun, Leilei Dai and Ming Shi

(582v) Electrospun Clay: Fabrication of Moldable 3-Dimensional Fibrous Scaffolds
Slgirim Lee, Sung Hwan Cho, Unyong Jeong and Jae-Hyung Jang

(582w) Copper Nanocluster Based Fluorescent Sensors for Sensitive and Selective Detection of Kojic Acid in Food Stuff
Zhao Gao, Wei Qi, Mengfan Wang, Rongxin Su and Zhimin He

(582x) Conversion of Racemic Profens to (S)-Profens
Saideh Mortazavi and James Salvador

(582y) Characterization of AmiBA2446, a Novel Bacteriolytic Enzyme Active Against Bacillus Species
Krunal Mehta
File available
(582z) Investigation of the Impact of Bioprocess Variables on Performance using Multivariate Analysis
Gregory Anderson, Anne Kantardjieff, David Osterman and Pratik Jaluria
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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