52 Receptor-Mediated Phenomena

Monday, October 29, 2012: 8:30 AM
Somerset West (Westin )
Description:
Cells sense and respond to their environment via receptor-mediated phenomena. In this session, we encourage talks that highlight spatial and dynamic aspects of receptor events, including the interplay between receptor trafficking and intracellular signaling, the coupling of mechanical stresses with cell signaling, receptor regulation, receptor-mediated therapeutic strategies, and cross-talk among receptor signaling pathways. Examples that integrate experiments with theory are particularly welcome.

Sponsor:
Engineering Fundamentals in Life Science

Chair:
Piyush Koria
Email: pkoria@usf.edu

Co-Chair:
Gregory T. Reeves
Email: gregreeves@ncsu.edu


8:30 AM
Break

8:48 AM
(52a) The Interaction of a Bacterial Toxin (Aggregatibacter actinomycetemcomitans leukotoxin) with Its Receptor Depends On Both Lipid-Protein and Protein-Protein Interactions
Angela C. Brown, Patrik Nygren, Kathleen Boesze-Battaglia and Edward T. Lally

9:06 AM
(52b) The Pivotal Role of Motifs: Elucidating Mechanisms of Heterologous GPCR Expression and Trafficking in Yeast Through Chimeric Receptors
Carissa L. Young, Emily C. McCusker, Zachary T. Britton, Shannon Modla, Jeffrey Caplan, Kirk J. Czymmek and Anne S. Robinson

9:24 AM
(52c) Silencing α(1,3)Fucosyltransferases in Human Leukocytes Reveals Differences in E-Selectin Ligand Synthesis Between Humans and Mice
Alexander Buffone Jr., Nandini Mondal, Kyle P. McHugh, Joseph T.Y. Lau and Sriram Neelamegham

9:42 AM
(52d) Analysis of Time Scales Involved in Ligand-Mediated Endocytosis of the EGF Receptor
Calixte S. Monast and Matthew J. Lazzara

10:00 AM
(52e) TLR4 Signals Via a Novel Allosteric Switch-Like Mechanism
Nichole Daringer and Joshua N. Leonard

10:18 AM
(52f) Feedback Control of Gene Expression in Tissue Patterning
Sophia Carrell

10:36 AM
(52g) Functional Single-Cell Analysis of T-Cell Activation by Supported Lipid Bilayer Tethered Ligands On Arrays of Nanowells
Alexis J. Torres, Rita Lucia Contento, Susana Gordo, Kai W. Wucherpfennig and J. Christopher Love

10:54 AM
(52h) Cell-Cell Contact Regulates Myogenic Fate Differentiation of Mesenchymal Stem Cell Through OB-Cadherin
Stella Alimperti and Stelios T. Andreadis
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture
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