467 Applications of Continuous Processing in Manufacture of Pharmaceuticals: Drug Substance

Wednesday, October 31, 2012: 12:30 PM
Allegheny III (Westin )
Description:
Pharmaceutical manufacturing has been dominated by the batch processing concept, where each unit dosage form is produced in a batch and tracked accordingly. However, over the last decade continuous manufacturing of active pharmaceutical ingredients (APIs) and drug products has become increasingly important as there are many advantages, such as reduced capital and operational costs, as well as real-time quality control for increased process reliability and reproducibility. Thus, this session invites speakers to present their scientific efforts in the area of continuous processing for API and drug product manufacturing.

Sponsor:
Pharmaceuticals

Chair:
Co-Chair:
Daniel Patience
Email: daniel.patience@tevapharm.com

- indicates paper has an Extended Abstract file available on CD.

File available
12:30 PM

12:51 PM

1:12 PM
(467c) Characterization and Selection of Continuous Plug Flow Reactors in Pharmaceutical Development
Brian D. Haeberle, Martin D. Johnson, Scott A. May, Timothy Braden and Ed Plocharczyk

1:33 PM
(467d) Multi Scale Flowsheet Simulation for the Purification and Processing of Active Pharmaceutical Ingredients
Maitraye Sen, Anwesha Chaudhury, Joyce John, Ravendra Singh and Rohit Ramachandran

2:15 PM
(467f) Sustainable and Continuous Reduction of Amides
Kathryn Rix, Geoffrey Kelsall, Klaus Hellgardt and Mimi Hii

2:36 PM
(467g) Benign Alkylation of Amines by Alcohols (AAA)
Luka Tallon, Klaus Hellgardt and Mimi Hii