75 Cell Culture I: Experimental

Monday, October 29, 2012: 12:30 PM
Washington (Westin )
Description:
This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, pharmaceuticals, vaccines and high-value secondary metabolites. Topics for this session focus on experimental methods which include, but are not limited to, cell line development and engineering, genomics, metabolomics and proteomics analysis, high throughput cell culture screening systems, media development, bioreactor design and operation scale-up and scale-down methodologies, improvement of yield recombinant protein or vaccines yield through process optimization, process characterization and control.

Sponsor:
Bioengineering

Chair:
Christie A.M. Peebles
Email: christie.peebles@colostate.edu

Co-chairs:
Ganesh Sriram
Email: gsriram@umd.edu

Gargi Ghosh
Email: gargi@umich.edu

Vijayakumar Janakiraman
Email: vijay.janakiraman@biogenidec.com

- indicates paper has an Extended Abstract file available on CD.


1:30 PM
(75d) Application of Multivariate Analysis Tools and Design of Experiments (DoE) to Model the Design Space for Characterization of a Mammalian Cell Culture Process
Vijayakumar Janakiraman, Benjamin Orbon, Yao-Ming Huang, Barry Wolf, Maartje Verschuur, Amit Varma, Marty Sinacore and Thomas Ryll

1:50 PM

2:20 PM
(75f) Microfluidic Scale-Down of Upstream Biopharmaceutical Production
Shireen Goh, Michelangelo Canzoneri, Horst Blum, Rajeev J. Ram and Anthony J. Sinskey
File available
2:40 PM
(75g) Enhancement of Cell Adhesion and Proliferation Through Surface Roughness Modification in CHO Cell Cultures in PMMA-PDMS Micro-Devices
Lucía D. Garza-García, Eduardo J. Tapia-Mejía, Erika García-López, Sergio Camacho-León, Ciro Angel Rodríguez-González, Leydi Maribel Carrillo-Cocom and Mario M. Alvarez