56 Systems and Synthetic Biology of Interacting Microorganisms

Monday, October 29, 2012: 8:30 AM
Washington (Westin )
Microorganisms (viruses, bacteria, and fungi) play critical roles in numerous natural processes associated with human health and the environment. Almost without exception, these microbes are engaged in extensive interactions with one another and/or with other species (e.g., their human host). With the rapid development of high throughput technologies (e.g., metagenomic sequencing) and related computational methods, the investigation of microbe-microbe and microbe-host interactions are defining new frontiers of systems biology. Moreover, emerging synthetic biology approaches have also started to capitalize on this research area of rich potential. This session will highlight original systems and synthetic biology approaches for understanding and engineering microbial interactions. Topics of interest include, but are not limited to: "omics" based study of microbial communities; modeling of microbe-host interactions; synthetic systems of interacting microbes; and engineering of microbial consortia. Subjects closely related to practical applications, including challenges related to the environment, bioprocessing and human health, are especially of interest.


Cynthia Collins
Email: ccollins@rpi.edu

Matthew J. Lazzara
Email: mlazzara@seas.upenn.edu

Ross P. Carlson
Email: rossc@biofilm.montana.edu

8:30 AM
(56a) Synthetic Autoinducer-2 Triggered Expression for Quorum Sensing Surveillance
Jessica Terrell, Hsuan Chen Wu, Chenyu Tsao, Matthew Servinsky and William Bentley

9:06 AM
(56c) Design and Construction of Synthetic Fungi-Bacteria Consortia for Direct Production of Isobutanol From Cellulosic Feedstocks
Jeremy J. Minty, Marc E. Singer, Chang Hoon Bae, Jungho Ahn, Cliff Foster, James C. Liao and Xiaoxia Lin

9:24 AM

10:18 AM
(56g) Synthetic Microbes Engineered to Fight Human Pathogens
Mui Hua Tan, Choon Kit Wong, Nazanin Saeidi, Tat-Ming Lo, In Young Hwang, Chueh Loo Poh and Matthew Wook Chang

10:36 AM
(56h) Inducible Cell Communication Amplifies Salmonella Gene Expression In Tumor Tissue
Neil S. Forbes, Yumei Dai, Charles Swofford and Bhushan J. Toley