557 Engineering Advances in Cancer Treatment

Wednesday, October 31, 2012: 3:15 PM
Pennsylvania East (Westin )
Cancer is a group of diseases characterized by genetic and other abnormalities leading to an imbalance between cell growth and programmed cell death (apoptosis). Even with advances in broad-spectrum and targeted (antibody-based) therapeutics, successes against this challenging disease remain few and highly focused on particular cancers. Engineers have a significant role to play in advancing the treatment of cancer from the genetic to the systemic scale and across the experimental-computational spectrum. Keys to these contributions are recognition of the clinical state-of-the-art, as well as constraints, defining and limiting potential interventions. Starting from this discussion, speakers from academia, the government, and industry will discuss challenge problems and potential solutions to understanding, analyzing, and treating cancer.

Biomedical Applications of Chemical Engineering
Engineering Fundamentals in Life Science (15d)

Robert Parker
Email: rparker@engr.pitt.edu

Neil S. Forbes
Email: forbes@ecs.umass.edu

- indicates paper has an Extended Abstract file available on CD.

3:15 PM
(557a) Cancer Cell Migration in 3D
Stephanie I. Fraley, Yunfeng Feng, Pei-Hsun Wu, Gregory Longmore and Denis Wirtz

4:18 PM
(557d) A Decision Tool for the Design of Optimal Personalised Chemotherapy Protocols for the Treatment of Acute Myeloid Leukaemia (AML)
Eleni Pefani, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C. Georgiadis and Efstratios N. Pistikopoulos

5:21 PM
(557g) Development and Characterization of Novel, Micelle-Based Parthenolide Delivery Systems
Michael Baranello, Hannah Watkins, Craig Jordan and Danielle Benoit