107 Pharmaceutical Process Development & Pilot Plants

Monday, October 29, 2012: 12:30 PM
Shadyside (Omni )
Pharmaceutical pilot plants are a valuable resource for ensuring efficient process scale-up and tech transfer to commercial manufacturing, as well as providing key deliveries of API and Drug Product for clinical supply. This session will showcase a variety of strategies for pilot plant design, operation, and even outsourcing that enhance pharmaceutical process development. Case studies on implementation of Process Analytical Technologies (PAT) in a pilot plant environment are also especially encouraged.

Pilot Plants
Pharmaceuticals (15b)

James Marek
Email: james.marek@abbott.com

Adam S. Butterbaugh, P.E.
Email: butterbaughas@lilly.com

- indicates paper has an Extended Abstract file available on CD.

12:51 PM
(107b) A Pharmaceutical Engineering Process/Product Life-Cycle Approach to Drug Product Development and Manufacturing
Jose C. Menezes, Stephan Sacher, Georg Scharrer, Stefan Leitgeb, Christine Voura, Simon D. Fraser and Johannes G. Khinast
File available
1:33 PM
(107d) Continuous Distillation Operations and Application of the Wiped Film Evaporator (WFE) to Pharmaceutical Pilot Plant Processing
Anne Mohan, Elizabeth Fisher, Rukyah Hennessey, Joe Kukura, Dave Lashen, Crystal Miranda, Glenn Spencer, Michael Ward, Ming Yue and George Zhou

1:54 PM

2:19 PM
(107f) Scale-up of Superficial Fluidization Air Velocity for a Pharmaceutical Fluid Bed Granulation
Brendon G. Ricart, Alan R. Silverman, Kristin J. Ploeger and Edward J. Smith
See more of this Group/Topical: Process Development Division