287373 Force Driven Separation of Particles and Drops by Deterministic Lateral Displacement

Monday, October 29, 2012
Hall B (Convention Center )
German Drazer, Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD

We present the separation of solid particles and drops in force-driven deterministic lateral displacement (f-DLD), a promising high-throughput continuous separation method in microfluidics. We perform both macroscopic experiments in scaled up systems as well as microfluidic experiments. The solid particles or drops are driven through a square array of cylindrical obstacles and, for some forcing orientations, they migrate in different directions. These experiments demonstrate the separation capabilities —and provide constraints for the design— of f-DLD for particles and drops of multiple sizes. We show that in all cases the trajectories of the particles follow selected locking directions in the lattice and present a simple collision model, based on particle-obstacle repulsive interactions, that accurately describes the trajectories of the particles for all forcing directions. Finally, we also demonstrate that a single line of cylindrical obstacles rotated with respect to the driving force is capable of performing binary separations. Using scaled up models proved to be a succesful approach to capture the behavior of microfluidic systems and test the deterministic limit.

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See more of this Session: Fluid Mechanics Poster Session
See more of this Group/Topical: Engineering Sciences and Fundamentals