276939 Electromagnetically Active Nanocomposite Metamaterial Biosensors

Friday, November 2, 2012: 9:42 AM
Washington (Westin )
D. Keith Roper, Chemical Engineering, University of Arkansas, Fayetteville, AR, Phillip Blake, Department of Chemical Engineering, University of Arkansas, Fayetteville, AR and Drew Dejarnette, Microelectronics/Photonics Graduate Program, University of Arkansas

Title: Electromagnetically active nanocomposite metamaterial biosensors

Abstract Body: Novel active biosensor platforms offer both sensitive detection and real-time characterization of biological targets in genomics, proteomics, and biomedical theranostic applications.  An example is quantized photon-exciton coupling which generates distance-dependent Forster resonance energy transfer in spectroscopic molecular rulers.  We have recently distinguished quantized plasmon polarizabilities which induce extraordinary opto-electronic coupling with phase-dependent photon diffraction in ordered metalloceramic nanocomposite metamaterialsMetamaterials exhibit tunable electromagnetic functionality -- from simple iridescence in butterfly wings to radiofrequency cloaking -- due to coherent interference from multidimensional structuring of suitable condensed-matter composites.  Sensitivity enhancement from tunable electromagnetic coupling in metamaterials appears more than 10-fold relative to sensitivities in conventional planar or nanoparticle sensors based on surface plasmon resonance.  Our lab has hybridized ‘top-down' lithography and ‘bottom-up' metallization approaches to fabricate nanocomposite metamaterial biosensor platforms.  Using scanning electron microscopy and microspectroscopy we show that prototype devices based on these platforms exhibit opto-electronic sensitivities consistent with model predictions.   These advances in modeling, fabrication, and prototype analysis are important milestones toward developing electromagnetically active nanocomposite metamaterials as biosensor platforms for next-generation disease diagnosis and personalized medicine.

Description: D_#_fig4

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See more of this Session: Micro and Nanofabricated Sensors
See more of this Group/Topical: Topical 9: Sensors